{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:54:07Z","timestamp":1791219247923,"version":"4.1.0"},"reference-count":24,"publisher":"International Union of Crystallography (IUCr)","issue":"10","license":[{"start":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:00:00Z","timestamp":1788566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:00:00Z","timestamp":1788566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25K01757"],"award-info":[{"award-number":["25K01757"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr C Struct Chem","Acta Crystallogr C","Acta Crystallogr C Cryst Struct Commun","Acta Cryst C","Acta Cryst C Struct Chem","Acta Cryst Sect C","Acta Cryst Sect C Struct Chem","Acta Crystallogr Sect C","Acta Crystallogr Sect C Struct Chem","Acta Crystallogr Sect C Cryst Struct Commun"],"accepted":{"date-parts":[[2026,8,28]]},"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:p>\n                    Fucoxanthin (C\n                    <jats:sub>42<\/jats:sub>\n                    H\n                    <jats:sub>58<\/jats:sub>\n                    O\n                    <jats:sub>6<\/jats:sub>\n                    ) is a highly functionalized allenic epoxy xanthophyll containing hydroxy, acetoxy, ketone and conjugated polyene units. Although its constitution and stereochemistry had been established by chemical, spectroscopic and synthetic studies, its small-molecule single-crystal X-ray structure has remained unavailable. Moss reported in 1979 [\n                    <jats:italic>Pure Appl. Chem.<\/jats:italic>\n                    (1979),\n                    <jats:bold>51<\/jats:bold>\n                    , 507\u2013514] that an early X-ray study by G. M. Sheldrick had reached only a partial solution of the fucoxanthin structure and that refinement had stalled at\n                    <jats:italic>R<\/jats:italic>\n                    \u2243 25%. The first small-molecule single-crystal X-ray structure of fucoxanthin has now been determined as the diethyl ether monosolvate, C\n                    <jats:sub>42<\/jats:sub>\n                    H\n                    <jats:sub>58<\/jats:sub>\n                    O\n                    <jats:sub>6<\/jats:sub>\n                    \u00b7C\n                    <jats:sub>4<\/jats:sub>\n                    H\n                    <jats:sub>10<\/jats:sub>\n                    O, at 100\u2005K in the space group\n                    <jats:italic>P<\/jats:italic>\n                    1 using synchrotron radiation (\u03bb\u00a0= 0.4132\u2005\u00c5). The asymmetric unit contains two crystallographically independent fucoxanthin molecules and two diethyl ether molecules. The structure defines the relative stereochemistry, allene geometry, epoxide geometry, polyene bond-length alternation and solvate-assisted packing of fucoxanthin, and provides an independent small-molecule metrical reference for comparison with protein-bound fucoxanthin ligands.\n                  <\/jats:p>","DOI":"10.1107\/s2053229626008946","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T07:39:11Z","timestamp":1788334751000},"page":"627-633","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":0,"title":["Crystal structure of fucoxanthin: resolving a long-standing crystallographic challenge"],"prefix":"10.1107","volume":"82","author":[{"given":"Yui","family":"Wakasa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao","family":"Minoura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2026,9,5]]},"reference":[{"key":"oj3044_bb1","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1107\/S0108768106052633","volume":"63","author":"Bartalucci","year":"2007","journal-title":"Acta Cryst. 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