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MIF regulates both adaptive and innate immune responses and contributes to the pathogenesis of parasitic infections, including malaria. Plasma concentrations of\n                    <jats:italic>P. vivax<\/jats:italic>\n                    MIF (\n                    <jats:italic>Pv<\/jats:italic>\n                    MIF) correlate with the severity of\n                    <jats:italic>P. vivax<\/jats:italic>\n                    malaria.\n                    <jats:italic>Plasmodium<\/jats:italic>\n                    spp. MIFs have been recognized as candidate malaria vaccines.\n                    <jats:italic>Pv<\/jats:italic>\n                    MIF, like other protozoan MIFs, binds to host CD74 and can suppress host MIF\u2013CD74 signaling. The production, crystallization and 1.8\u2005\u00c5 resolution structure of\n                    <jats:italic>Pv<\/jats:italic>\n                    MIF (PDB entry 9b0m, pdb_00009b0m) are reported.\n                    <jats:italic>Pv<\/jats:italic>\n                    MIF crystallized in space group\n                    <jats:italic>P<\/jats:italic>\n                    6\n                    <jats:sub>3<\/jats:sub>\n                    with a single molecule in the asymmetric unit. The biological unit of\n                    <jats:italic>Pv<\/jats:italic>\n                    MIF is the prototypical MIF trimer.\n                  <\/jats:p>","DOI":"10.1107\/s2053230x26003870","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:14:43Z","timestamp":1777889683000},"page":"194-200","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":1,"title":["Crystal structure of\n                    <i>Plasmodium vivax<\/i>\n                    macrophage migration inhibitory factor"],"prefix":"10.1107","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9867-6297","authenticated-orcid":true,"given":"Aryana","family":"Nair","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arav","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0833-3259","authenticated-orcid":true,"given":"Kevin","family":"Battaile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0017-2705","authenticated-orcid":true,"given":"Elizabeth","family":"Harmon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0056-0513","authenticated-orcid":true,"given":"Peter J.","family":"Myler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9570-5086","authenticated-orcid":true,"given":"Bart L.","family":"Staker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3215-4472","authenticated-orcid":true,"given":"Scott","family":"Lovell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4539-3971","authenticated-orcid":true,"given":"Graham","family":"Chakafana","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05fde5z47","id-type":"ROR","asserted-by":"publisher"}],"department":["Chemistry and Biochemistry"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4043-2700","authenticated-orcid":true,"given":"Oluwatoyin A.","family":"Asojo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"ada5001_bb1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ymeth.2011.07.005","volume":"55","author":"Adams","year":"2011","journal-title":"Methods"},{"key":"ada5001_bb2","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1107\/S2059798323003595","volume":"79","author":"Agirre","year":"2023","journal-title":"Acta Cryst. 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