{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T08:49:28Z","timestamp":1736844568446,"version":"3.33.0"},"reference-count":10,"publisher":"International Union of Crystallography (IUCr)","issue":"2","license":[{"start":{"date-parts":[[2015,1,31]],"date-time":"2015-01-31T00:00:00Z","timestamp":1422662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/uk\/legalcode"},{"start":{"date-parts":[[2015,1,31]],"date-time":"2015-01-31T00:00:00Z","timestamp":1422662400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/uk\/legalcode"}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"published-print":{"date-parts":[[2015,2,1]]},"abstract":"<jats:p>The title compound, C<jats:sub>19<\/jats:sub>H<jats:sub>29<\/jats:sub>NO<jats:sub>4<\/jats:sub>S, was synthesised from 9\u03b1-hydroxyparthenolide (9\u03b1-hydroxy-4,8-dimethyl-12-methylene-3,14-dioxatricyclo[9.3.0.0<jats:sup>2,4<\/jats:sup>]tetradec-7-en-13-one), which was isolated from the chloroform extract of the aerial parts of the plant<jats:italic>Anvillea radiata<\/jats:italic>. The molecule is built up from two fused five- and ten-membered rings, with an additional epoxy ring system and a thiomorpholine group as a substituent. The ten-membered ring adopts an approximate chair\u2013chair conformation, while the thiomorpholine ring displays a chair conformation and the five-membered ring has an envelope conformation, with the C atom closest to the hydroxy group forming the flap. An intramolecular O\u2014H...N hydrogen bond closes an<jats:italic>S<\/jats:italic>(8) ring. The crystal structure features weak C\u2014H...O hydrogen-bonding interactions, which link the molecules into [010] chains.<\/jats:p>","DOI":"10.1107\/s205698901500170x","type":"journal-article","created":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T09:49:51Z","timestamp":1422611391000},"page":"o140-o141","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":0,"title":["Crystal structure of (1<i>S<\/i>,2<i>R<\/i>,4<i>R<\/i>,9<i>S<\/i>,11<i>S<\/i>,12<i>R<\/i>)-9\u03b1-hydroxy-4,8-dimethyl-12-[(thiomorpholin-4-yl)methyl]-3,14-dioxatricyclo[9.3.0.0<sup>2,4<\/sup>]tetradec-7-en-13-one"],"prefix":"10.1107","volume":"71","author":[{"given":"Ahmed","family":"Benharref","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Akssira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lahcen","family":"El Ammari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Saadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moha","family":"Berraho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2015,1,31]]},"reference":[{"key":"hb7355_bb1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1021\/np960064g","volume":"59","author":"Abdel Sattar","year":"1996","journal-title":"J. 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