{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T05:18:10Z","timestamp":1736831890470,"version":"3.33.0"},"reference-count":19,"publisher":"International Union of Crystallography (IUCr)","issue":"10","license":[{"start":{"date-parts":[[2015,9,17]],"date-time":"2015-09-17T00:00:00Z","timestamp":1442448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/uk\/legalcode"},{"start":{"date-parts":[[2015,9,17]],"date-time":"2015-09-17T00:00:00Z","timestamp":1442448000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/uk\/legalcode"}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"published-print":{"date-parts":[[2015,10,1]]},"abstract":"<jats:p>In the title compound, phenyl (<jats:italic>S<\/jats:italic>)-2-[(<jats:italic>S<\/jats:italic>)-(1-{2-[(<jats:italic>S<\/jats:italic>)-(1-{[(<jats:italic>tert<\/jats:italic>-butoxy)carbonyl]amino}bicyclo[2.2.2]octan-2-yl)formamido]propanamido}bicyclo[2.2.2]octan-2-yl)formamido]-3-phenylpropanoate chloroform monosolvate, C<jats:sub>42<\/jats:sub>H<jats:sub>56<\/jats:sub>N<jats:sub>4<\/jats:sub>O<jats:sub>7<\/jats:sub>\u00b7CHCl<jats:sub>3<\/jats:sub>, the \u03b1,\u03b2-hybrid peptide contains two non-proteinogenic amino acid residues of (<jats:italic>S<\/jats:italic>)-1-aminobicyclo[2.2.2]octane-2-carboxylic acid [(<jats:italic>S<\/jats:italic>)-ABOC], two amino acid residues of (<jats:italic>S<\/jats:italic>)-2-aminopropanoic acid [(<jats:italic>S<\/jats:italic>)-Ala] and (<jats:italic>S<\/jats:italic>)-2-amino-3-phenylpropanoic acid [(<jats:italic>S<\/jats:italic>)-Phe], and protecting groups of<jats:italic>tert<\/jats:italic>-butoxycarbonyl (Boc) and benzyl ester (OBn). The tetramer folds into a right-handed mixed 11\/9 helix stabilized by intramolecular<jats:italic>i<\/jats:italic>,<jats:italic>i<\/jats:italic>\u00a0+\u00a03 and<jats:italic>i<\/jats:italic>,<jats:italic>i<\/jats:italic>\u00a0\u2212\u00a01 C=O...H\u2014N hydrogen bonds. In the crystal, the oligomers are linked by N\u2014H...O=C hydrogen bonds into chains along the<jats:italic>a-<\/jats:italic>axis direction. The chloroform solvent molecules are intercalated between the folded chains<jats:italic>via<\/jats:italic>C\u2014H...O=C interactions.<\/jats:p>","DOI":"10.1107\/s2056989015016941","type":"journal-article","created":{"date-parts":[[2015,9,22]],"date-time":"2015-09-22T19:25:42Z","timestamp":1442949942000},"page":"1193-1195","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":0,"title":["Crystal structure of Boc-(<i>S<\/i>)-ABOC-(<i>S<\/i>)-Ala-(<i>S<\/i>)-ABOC-(<i>S<\/i>)-Phe-OBn chloroform monosolvate"],"prefix":"10.1107","volume":"71","author":[{"given":"Emmanuel","family":"Wenger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure","family":"Moulat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baptiste","family":"Legrand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muriel","family":"Amblard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique","family":"Calm\u00e8s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claude","family":"Didierjean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2015,9,17]]},"reference":[{"key":"is5415_bb1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1107\/S0021889804003528","volume":"37","author":"Allen","year":"2004","journal-title":"J. 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