{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T23:10:15Z","timestamp":1767913815622,"version":"3.49.0"},"reference-count":0,"publisher":"International Union of Crystallography (IUCr)","issue":"10","license":[{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"funder":[{"DOI":"10.13039\/501100007684","name":"Ministry of Education and Science of Ukraine","doi-asserted-by":"publisher","award":["0121U107777"],"award-info":[{"award-number":["0121U107777"]}],"id":[{"id":"10.13039\/501100007684","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"accepted":{"date-parts":[[2021,9,20]]},"published-print":{"date-parts":[[2021,10,1]]},"abstract":"<jats:p>The title compound, C<jats:sub>15<\/jats:sub>H<jats:sub>18<\/jats:sub>N<jats:sub>4<\/jats:sub>O<jats:sub>2<\/jats:sub>, was obtained <jats:italic>via<\/jats:italic> a two-step synthesis (Dimroth reaction and amidation) for anticancer activity screening and was selected from a 1<jats:italic>H<\/jats:italic>-1,2,3-triazole-4-carboxamide library. The cyclopropyl ring is oriented almost perpendicular to the benzene ring [dihedral angle = 87.9\u2005(1)\u00b0], while the dihedral angle between the mean plane of the cyclopropyl ring and that of the triazole ring is 55.6\u2005(1)\u00b0. In the crystal, the molecules are linked by O\u2014H...O and C\u2014H...N interactions into infinite ribbons propagating in the [001] direction, which are interconnected by weak C\u2014H...O interactions into layers. The intermolecular interactions were characterized <jats:italic>via<\/jats:italic> Hirshfeld surface analysis, which indicated that the largest fingerprint contact percentages are H...H (55.5%), N...H\/H...N (15.4%), C...H\/H...C (13.2%) and O...H\/H...O (12.9%).<\/jats:p>","DOI":"10.1107\/s2056989021009774","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T08:47:06Z","timestamp":1632818826000},"page":"1043-1047","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":3,"title":["Synthesis, crystal structure and Hirshfeld surface analysis of 5-cyclopropyl-<i>N<\/i>-(2-hydroxyethyl)-1-(4-methylphenyl)-1<i>H<\/i>-1,2,3-triazole-4-carboxamide"],"prefix":"10.1107","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8222-5008","authenticated-orcid":true,"given":"Nazariy T.","family":"Pokhodylo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yurii","family":"Slyvka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volodymyr","family":"Pavlyuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2021,9,28]]},"container-title":["Acta Crystallographica Section E Crystallographic Communications"],"original-title":[],"link":[{"URL":"http:\/\/journals.iucr.org\/e\/issues\/2021\/10\/00\/hb7983\/hb7983.pdf","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.iucr.org\/e\/issues\/2021\/10\/00\/hb7983\/hb7983.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T10:40:15Z","timestamp":1736764815000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.iucr.org\/paper?S2056989021009774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,28]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2021,10]]}},"alternative-id":["S2056989021009774"],"URL":"https:\/\/doi.org\/10.1107\/s2056989021009774","relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.1107\/S2056989021009774\/hb7983sup1.cif","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989021009774\/hb7983Isup2.hkl","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989021009774\/hb7983Isup3.mol","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989021009774\/hb7983Isup4.cml","asserted-by":"subject"}]},"ISSN":["2056-9890"],"issn-type":[{"value":"2056-9890","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,28]]},"assertion":[{"value":"Acta Crystallographica Section E: Crystallographic Communications","order":0,"name":"journal","label":"Publication","explanation":{"URL":"http:\/\/journals.iucr.org\/e"},"group":{"name":"general","label":"General"}},{"value":"research communications","order":1,"name":"content_type","label":"Content type","explanation":{"URL":"https:\/\/journals.iucr.org\/e\/services\/notesforauthors.html"},"group":{"name":"general","label":"General"}},{"value":"Available","URL":"https:\/\/scripts.iucr.org\/cgi-bin\/citedin?hb7983","order":2,"name":"article_metrics","label":"Article metrics","group":{"name":"general","label":"General"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"6 September 2021","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication history"}},{"value":"20 September 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication history"}},{"value":"28 September 2021","order":2,"name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication history"}},{"value":"This article has supporting information","name":"supplementary_materials","label":"Supplementary materials","explanation":{"URL":"https:\/\/scripts.iucr.org\/cgi-bin\/sendsup?hb7983"}},{"value":"\u00a9 2021 Pokhodylo et al.","order":0,"name":"copyright","label":"Copyright","explanation":{"URL":"http:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}},{"value":"Creative Commons Attribution (CC-BY)","order":1,"name":"license","label":"Licence","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}}]}}