{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T04:16:18Z","timestamp":1778300178310,"version":"3.51.4"},"reference-count":29,"publisher":"International Union of Crystallography (IUCr)","issue":"2","license":[{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"accepted":{"date-parts":[[2022,1,2]]},"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:p>The title cyclobutyl compound, C<jats:sub>18<\/jats:sub>H<jats:sub>18<\/jats:sub>N<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub>S, was synthesized by the interaction of 4-(3-methyl-3-phenylcyclobutyl)thiazol-2-amine and maleic anhydride, and crystallizes in the orthorhombic space group <jats:italic>P<\/jats:italic>2<jats:sub>1<\/jats:sub>2<jats:sub>1<\/jats:sub>2<jats:sub>1<\/jats:sub> with <jats:italic>Z<\/jats:italic>\u2032 = 1. The molecular geometry is partially stabilized by an intramolecular N\u2014H...O hydrogen bond forming an <jats:italic>S<\/jats:italic>\n                  <jats:sub>1<\/jats:sub>\n                  <jats:sup>1<\/jats:sup>(7) ring motif. The molecule is non-planar with a dihedral angle of 88.29\u2005(11)\u00b0 between the thiazole and benzene rings. In the crystal, the molecules are linked by O\u2014H...N hydrogen bonds, forming supramolecular ribbons with <jats:italic>C<\/jats:italic>\n                  <jats:sub>1<\/jats:sub>\n                  <jats:sup>1<\/jats:sup>(9) chain motifs. To further analyze the intermolecular interactions, a Hirshfeld surface analysis was performed. The results indicate that the most important contributions to the overall surface are from H...H (43%), C...H (18%), O...H (17%) and N...H (6%), interactions.<\/jats:p>","DOI":"10.1107\/s2056989022000032","type":"journal-article","created":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T09:55:54Z","timestamp":1641549354000},"page":"120-124","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":15,"title":["Crystal structure and Hirshfeld surface analysis of (<i>Z<\/i>)-4-{[4-(3-methyl-3-phenylcyclobutyl)thiazol-2-yl]amino}-4-oxobut-2-enoic acid"],"prefix":"10.1107","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1157-4088","authenticated-orcid":true,"given":"Okan","family":"Simsek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muharrem","family":"Dincer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0660-4721","authenticated-orcid":true,"given":"Necmi","family":"Dege","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiad","family":"Saif","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8297-2350","authenticated-orcid":true,"given":"Alaaddin","family":"Cukurovali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2022,1,7]]},"reference":[{"key":"jq2012_bb1","doi-asserted-by":"crossref","first-page":"127654","DOI":"10.1016\/j.molstruc.2019.127654","volume":"1205","author":"Albayati","year":"2020","journal-title":"J. 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