{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T09:33:38Z","timestamp":1759743218104,"version":"3.37.3"},"reference-count":9,"publisher":"International Union of Crystallography (IUCr)","issue":"9","license":[{"start":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T00:00:00Z","timestamp":1659398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T00:00:00Z","timestamp":1659398400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"accepted":{"date-parts":[[2022,7,26]]},"published-print":{"date-parts":[[2022,9,1]]},"abstract":"<jats:p>An easily accessible experimental set-up to grow large single crystals of two sweeteners readily available in supermarkets, erythritol and xylitol, is described. The crystallization of these compounds illustrates the principles of crystallization by evaporation. As these artificial sweeteners are also known to induce a cool sensation in the mouth, the crystal-growing experiment is complemented with a simple calorimetric set-up to demonstrate the endothermic nature of the dissolution of the selected sweeteners in a more quantitative approach by measuring the heat of dissolution (\u0394<jats:italic>H<\/jats:italic>\n                  <jats:sub>diss<\/jats:sub>). The choice of these two sweeteners also allows use of the freely available WebCSD and <jats:italic>Mercury<\/jats:italic> tools to visualize their three-dimensional structure, crystal packing and powder diffractograms, and to deepen stereochemical concepts such as stereoisomers and <jats:italic>meso<\/jats:italic> compounds.<\/jats:p>","DOI":"10.1107\/s2056989022007617","type":"journal-article","created":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T10:08:46Z","timestamp":1659434926000},"page":"874-879","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":4,"title":["Classroom experiments with artificial sweeteners: growing single crystals and simple calorimetry"],"prefix":"10.1107","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4920-6857","authenticated-orcid":true,"given":"Johan","family":"Wouters","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2186-5209","authenticated-orcid":true,"given":"Luc","family":"Van Meervelt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2022,8,2]]},"reference":[{"key":"pk2668_bb1","doi-asserted-by":"crossref","first-page":"3079","DOI":"10.1107\/S0567740880010825","volume":"36","author":"Ceccarelli","year":"1980","journal-title":"Acta Cryst. B"},{"key":"pk2668_bb2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1107\/S2052520616003954","volume":"72","author":"Groom","year":"2016","journal-title":"Acta Cryst. B"},{"key":"pk2668_bb3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0008-6215(92)80002-I","volume":"223","author":"Jeffrey","year":"1992","journal-title":"Carbohydr. Res."},{"key":"pk2668_bb4","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0008-6215(93)84246-3","volume":"247","author":"Kopf","year":"1993","journal-title":"Carbohydr. Res."},{"key":"pk2668_bb5","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1107\/S1600576719014092","volume":"53","author":"Macrae","year":"2020","journal-title":"J. Appl. Cryst."},{"key":"pk2668_bb6","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1107\/S010876810301557X","volume":"59","author":"Madsen","year":"2003","journal-title":"Acta Cryst. B"},{"key":"pk2668_bb7","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1021\/ja01133a522","volume":"74","author":"Parks","year":"1952","journal-title":"J. Am. Chem. Soc."},{"key":"pk2668_bb8","doi-asserted-by":"crossref","first-page":"C1044","DOI":"10.1107\/S2053273314089554","volume":"70","author":"Van Meervelt","year":"2014","journal-title":"Acta Cryst. A"},{"key":"pk2668_bb9","doi-asserted-by":"crossref","first-page":"C510","DOI":"10.1107\/S2053273317090635","volume":"73","author":"Van Meervelt","year":"2017","journal-title":"Acta Cryst. A"}],"container-title":["Acta Crystallographica Section E Crystallographic Communications"],"original-title":[],"link":[{"URL":"http:\/\/journals.iucr.org\/e\/issues\/2022\/09\/00\/pk2668\/pk2668.pdf","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.iucr.org\/e\/issues\/2022\/09\/00\/pk2668\/pk2668.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T11:11:27Z","timestamp":1736766687000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.iucr.org\/paper?S2056989022007617"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,2]]},"references-count":9,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2022,9]]}},"alternative-id":["S2056989022007617"],"URL":"https:\/\/doi.org\/10.1107\/s2056989022007617","relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.1107\/S2056989022007617\/pk2668sup1.png","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989022007617\/pk2668sup2.png","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989022007617\/pk2668sup3.png","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989022007617\/pk2668sup4.png","asserted-by":"subject"}]},"ISSN":["2056-9890"],"issn-type":[{"type":"electronic","value":"2056-9890"}],"subject":[],"published":{"date-parts":[[2022,8,2]]},"assertion":[{"value":"Acta Crystallographica Section E: Crystallographic Communications","order":0,"name":"journal","label":"Publication","explanation":{"URL":"http:\/\/journals.iucr.org\/e"},"group":{"name":"general","label":"General"}},{"value":"research communications","order":1,"name":"content_type","label":"Content type","explanation":{"URL":"https:\/\/journals.iucr.org\/e\/services\/notesforauthors.html"},"group":{"name":"general","label":"General"}},{"value":"Available","URL":"https:\/\/scripts.iucr.org\/cgi-bin\/citedin?pk2668","order":2,"name":"article_metrics","label":"Article metrics","group":{"name":"general","label":"General"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"13 July 2022","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication history"}},{"value":"26 July 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication history"}},{"value":"2 August 2022","order":2,"name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication history"}},{"value":"This article has supporting information","name":"supplementary_materials","label":"Supplementary materials","explanation":{"URL":"https:\/\/scripts.iucr.org\/cgi-bin\/sendsup?pk2668"}},{"value":"\u00a9 2022 Wouters and Van Meervelt","order":0,"name":"copyright","label":"Copyright","explanation":{"URL":"http:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}},{"value":"Creative Commons Attribution (CC-BY)","order":1,"name":"license","label":"Licence","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}}]}}