{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:48:32Z","timestamp":1785422912190,"version":"3.56.0"},"reference-count":0,"publisher":"International Union of Crystallography (IUCr)","issue":"3","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"funder":[{"DOI":"10.13039\/100000183","name":"Army Research Office","doi-asserted-by":"crossref","award":["W911NF-16-P-0029"],"award-info":[{"award-number":["W911NF-16-P-0029"]}],"id":[{"id":"10.13039\/100000183","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"accepted":{"date-parts":[[2023,2,3]]},"published-print":{"date-parts":[[2023,3,1]]},"abstract":"\n The complex, bis(\n N<\/jats:italic>\n ,\n N<\/jats:italic>\n -diethyl-4-methyl-4-piperazine-1-carboxamide) tetrakis(isothiocyanato-\u03ba\n N<\/jats:italic>\n )cobalt(II) (\n N<\/jats:italic>\n ,\n N<\/jats:italic>\n -diethyl-4-methyl-4-piperazine-1-carboxamide = diethylcarbamazine), (C\n 10<\/jats:sub>\n H\n 22<\/jats:sub>\n N\n 3<\/jats:sub>\n O)\n 2<\/jats:sub>\n [Co(NCS)\n 4<\/jats:sub>\n ], is presented. This complex is a blue precipitate, insoluble in water but soluble in organic solvents, that is formed from the reaction of diethylcarbamazine citrate, a protonated tertiary amine, with cobalt(II) and thiocyanate. This reaction, in the form of the Scott test, is a common presumptive test for cocaine hydrochloride. The known cobalt compound, [K\n 2<\/jats:sub>\n Co(NCS)\n 4<\/jats:sub>\n ]\u00b73H\n 2<\/jats:sub>\n O, has a deep-blue coloration due to the tetrahedral [Co(NCS)\n 4<\/jats:sub>\n ]\n 2\u2212<\/jats:sup>\n that is also present in the ion pair with bulky amines, and is similar to the color of other tetrahedral cobalt(II) complex ions, such as [CoCl\n 4<\/jats:sub>\n ]\n 2\u2212<\/jats:sup>\n . The structure is consistent with a previous proposal that a hydrophobic ion pair formed between [Co(NCS)\n 4<\/jats:sub>\n ]\n 2\u2212<\/jats:sup>\n and two protonated molecules of cocaine is responsible for the blue hydrophobic products formed by cocaine in the Scott test.\n <\/jats:p>","DOI":"10.1107\/s2056989023000981","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T11:09:42Z","timestamp":1675940982000},"page":"163-166","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":2,"title":["Bis(\n N<\/i>\n ,\n N<\/i>\n -diethyl-4-methyl-4-piperazine-1-carboxamide) tetrakis(isothiocyanato-\u03ba\n N<\/i>\n )cobalt(II), a model compound for the blue color developed in the Scott test"],"prefix":"10.1107","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0511-1127","authenticated-orcid":true,"given":"Allen G.","family":"Oliver","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00mkhxb43","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy-Lynn E.","family":"Lockwood","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00mkhxb43","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Zinna","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00mkhxb43","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marya","family":"Lieberman","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00mkhxb43","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2023,2,9]]},"container-title":["Acta Crystallographica Section E Crystallographic Communications"],"original-title":[],"link":[{"URL":"https:\/\/journals.iucr.org\/e\/issues\/2023\/03\/00\/zl5041\/zl5041.pdf","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.iucr.org\/e\/issues\/2023\/03\/00\/zl5041\/zl5041.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T06:16:01Z","timestamp":1736748961000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.iucr.org\/paper?S2056989023000981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,9]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["S2056989023000981"],"URL":"https:\/\/doi.org\/10.1107\/s2056989023000981","relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.1107\/S2056989023000981\/zl5041sup1.cif","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989023000981\/zl5041Isup2.hkl","asserted-by":"subject"}]},"ISSN":["2056-9890"],"issn-type":[{"value":"2056-9890","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,9]]},"assertion":[{"value":"Acta Crystallographica Section E: Crystallographic Communications","order":0,"name":"journal","label":"Publication","explanation":{"URL":"https:\/\/journals.iucr.org\/e"},"group":{"name":"general","label":"General"}},{"value":"research communications","order":1,"name":"content_type","label":"Content type","explanation":{"URL":"https:\/\/journals.iucr.org\/e\/services\/notesforauthors.html"},"group":{"name":"general","label":"General"}},{"value":"Available","URL":"https:\/\/scripts.iucr.org\/cgi-bin\/citedin?zl5041","order":2,"name":"article_metrics","label":"Article metrics","group":{"name":"general","label":"General"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"21 December 2022","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication history"}},{"value":"3 February 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication history"}},{"value":"9 February 2023","order":2,"name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication history"}},{"value":"This article has supporting information","name":"supplementary_materials","label":"Supplementary materials","explanation":{"URL":"https:\/\/scripts.iucr.org\/cgi-bin\/sendsup?zl5041"}},{"value":"\u00a9 2023 Oliver\n et al.","order":0,"name":"copyright","label":"Copyright","explanation":{"URL":"https:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}},{"value":"Creative Commons Attribution (CC-BY)","order":1,"name":"license","label":"Licence","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}}]}}