{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:11:00Z","timestamp":1785424260516,"version":"3.56.0"},"reference-count":22,"publisher":"International Union of Crystallography (IUCr)","issue":"4","license":[{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"accepted":{"date-parts":[[2023,3,8]]},"published-print":{"date-parts":[[2023,4,1]]},"abstract":"<jats:p>\n                    The 2:1 co-crystal of nadifloxacin [systematic name: 9-fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-6,7-dihydro-1\n                    <jats:italic>H<\/jats:italic>\n                    ,5\n                    <jats:italic>H<\/jats:italic>\n                    -pyrido[3,2,1-\n                    <jats:italic>ij<\/jats:italic>\n                    ]quinoline-2-carboxylic acid] with oxalic acid, C\n                    <jats:sub>19<\/jats:sub>\n                    H\n                    <jats:sub>21<\/jats:sub>\n                    FN\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>4<\/jats:sub>\n                    \u00b70.5C\n                    <jats:sub>2<\/jats:sub>\n                    H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>4<\/jats:sub>\n                    , was prepared by slow evaporation from a chloroform:acetone solvent system. Nadifloxacin belongs to the group of antibacterial drugs. The co-crystal is stabilized through an intramolecular O\u2014H...O bond and intermolecular hydrogen bonds. It was studied by FT\u2013IR spectroscopy, differential scanning calorimetry and X-ray diffraction. Hirshfeld surface analysis indicated that the major contribution to the packing is from O...H\/H...O interactions.\n                  <\/jats:p>","DOI":"10.1107\/s2056989023002244","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T03:58:53Z","timestamp":1678420733000},"page":"319-322","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":3,"title":["Co-crystal of nadifloxacin with oxalic acid"],"prefix":"10.1107","volume":"79","author":[{"given":"Geethanjali N.","family":"Karthammaiah","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xapxe37","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreenivasa","family":"Rao Amaraneni","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xapxe37","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand K.","family":"Solomon","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xapxe37","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2023,3,10]]},"reference":[{"key":"mw2196_bb1","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1107\/S2056989019013859","volume":"75","author":"Bairagi","year":"2019","journal-title":"Acta Cryst. E"},{"key":"mw2196_bb2","unstructured":"Bruker (2016). APEX3, SAINT, XPREP and SADABS. Bruker AXS Inc. Madison, Wisconsin, USA."},{"key":"mw2196_bb3","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1107\/S0108768189012929","volume":"46","author":"Etter","year":"1990","journal-title":"Acta Cryst. B"},{"key":"mw2196_bb4","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1107\/S0021889812029111","volume":"45","author":"Farrugia","year":"2012","journal-title":"J. Appl. Cryst."},{"key":"mw2196_bb5","doi-asserted-by":"crossref","first-page":"4963","DOI":"10.1021\/cg300895c","volume":"12","author":"Gangavaram","year":"2012","journal-title":"Cryst. Growth Des."},{"key":"mw2196_bb6","doi-asserted-by":"crossref","unstructured":"Kido, M. & Hashimoto, K. (1994). Chem. Pharm. Bull. 42, 4, 872-876. Vol. 42 No. 4. DOI: 10.1248\/cpb. 42.872","DOI":"10.1248\/cpb.42.872"},{"key":"mw2196_bb7","doi-asserted-by":"crossref","unstructured":"Kumar, P. & Khatak, S. (2021). Int. Res. J. Pharm. 12, 4, 23-33. DOI: 10.7897\/2230-8407.1204130.","DOI":"10.7897\/2230-8407.1204130"},{"key":"mw2196_bb8","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1107\/S1600576719014092","volume":"53","author":"Macrae","year":"2020","journal-title":"J. Appl. Cryst."},{"key":"mw2196_bb9","doi-asserted-by":"crossref","first-page":"5582","DOI":"10.1039\/D1CC07187D","volume":"58","author":"Mannava","year":"2022","journal-title":"Chem. Commun."},{"key":"mw2196_bb10","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1039\/D0CE01316A","volume":"23","author":"Mannava","year":"2021","journal-title":"CrystEngComm"},{"key":"mw2196_bb11","doi-asserted-by":"crossref","unstructured":"Nangia, A., Gunnam, A. & Kuthuru, S. (2018). Cryst. Growth Des. 18, 5, 2824-2835.","DOI":"10.1021\/acs.cgd.7b01600"},{"key":"mw2196_bb12","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1159\/000081032","volume":"50","author":"Nenoff","year":"2004","journal-title":"Chemotherapy"},{"key":"mw2196_bb13","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1021\/acs.cgd.1c01509","volume":"22","author":"O'Malley","year":"2022","journal-title":"Cryst. Growth Des."},{"key":"mw2196_bb14","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.1002\/jps.22537","volume":"100","author":"Reddy","year":"2011","journal-title":"J. Pharm. Sci."},{"key":"mw2196_bb15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053273314026370","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Cryst. A"},{"key":"mw2196_bb16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053229614024218","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Cryst. C"},{"key":"mw2196_bb17","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1039\/B818330A","volume":"11","author":"Spackman","year":"2009","journal-title":"CrystEngComm"},{"key":"mw2196_bb18","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1107\/S1600576721002910","volume":"54","author":"Spackman","year":"2021","journal-title":"J. Appl. Cryst."},{"key":"mw2196_bb19","doi-asserted-by":"crossref","unstructured":"Stahly, G. P. (2009). Cryst. Growth Des. 9, 10, 4212-4229. DOI: 10.1021\/cg900873t.","DOI":"10.1021\/cg900873t"},{"key":"mw2196_bb20","doi-asserted-by":"crossref","first-page":"128806","DOI":"10.1016\/j.molstruc.2020.128806","volume":"20","author":"Suresh","year":"2020","journal-title":"J. Mol. Struct."},{"key":"mw2196_bb21","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/jps.20578","volume":"95","author":"Vishweshwar","year":"2006","journal-title":"J. Pharm. Sci."},{"key":"mw2196_bb22","doi-asserted-by":"crossref","first-page":"133335","DOI":"10.1016\/j.molstruc.2022.133335","volume":"1265","author":"Yang","year":"2022","journal-title":"J. Mol. Struct."}],"container-title":["Acta Crystallographica Section E Crystallographic Communications"],"original-title":[],"link":[{"URL":"https:\/\/journals.iucr.org\/e\/issues\/2023\/04\/00\/mw2196\/mw2196.pdf","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.iucr.org\/e\/issues\/2023\/04\/00\/mw2196\/mw2196.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T06:16:47Z","timestamp":1736749007000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.iucr.org\/paper?S2056989023002244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,10]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["S2056989023002244"],"URL":"https:\/\/doi.org\/10.1107\/s2056989023002244","relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.1107\/S2056989023002244\/mw2196sup1.cif","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989023002244\/mw2196Isup2.hkl","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989023002244\/mw2196Isup3.cml","asserted-by":"subject"}]},"ISSN":["2056-9890"],"issn-type":[{"value":"2056-9890","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,10]]},"assertion":[{"value":"Acta Crystallographica Section E: Crystallographic Communications","order":0,"name":"journal","label":"Publication","explanation":{"URL":"https:\/\/journals.iucr.org\/e"},"group":{"name":"general","label":"General"}},{"value":"research communications","order":1,"name":"content_type","label":"Content type","explanation":{"URL":"https:\/\/journals.iucr.org\/e\/services\/notesforauthors.html"},"group":{"name":"general","label":"General"}},{"value":"Available","URL":"https:\/\/scripts.iucr.org\/cgi-bin\/citedin?mw2196","order":2,"name":"article_metrics","label":"Article metrics","group":{"name":"general","label":"General"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"8 February 2023","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication history"}},{"value":"8 March 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication history"}},{"value":"10 March 2023","order":2,"name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication history"}},{"value":"This article has supporting information","name":"supplementary_materials","label":"Supplementary materials","explanation":{"URL":"https:\/\/scripts.iucr.org\/cgi-bin\/sendsup?mw2196"}},{"value":"\u00a9 2023 Karthammaiah\n                      et al.","order":0,"name":"copyright","label":"Copyright","explanation":{"URL":"https:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}},{"value":"Creative Commons Attribution (CC-BY)","order":1,"name":"license","label":"Licence","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}}]}}