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This compound has three tautomeric forms, which relative energies were estimated with quantum-chemical calculations. All these tautomers (dienol form<jats:bold>7A<\/jats:bold>, keto\u2013enol form<jats:bold>7B<\/jats:bold>, and diketo form<jats:bold>7C<\/jats:bold>) were optimized by the M06\u20132X\/cc-pVTZ method in a vacuum, using the PCM model with chloroform and DMSO as solvent. The diketo form of the title compound proved to be the most energetically favourable as compared to the keto\u2013enol or dienol forms. The diketo form can exist as three possible stereoisomers with the same configuration of one stereogenic center and different configurations of the stereogenic centers at two other atoms:<jats:bold>(<\/jats:bold><jats:italic><jats:bold>R<\/jats:bold><\/jats:italic>,<jats:italic><jats:bold>R<\/jats:bold><\/jats:italic>,<jats:italic><jats:bold>R<\/jats:bold><\/jats:italic><jats:bold>)<\/jats:bold>,<jats:bold>(<jats:italic>S<\/jats:italic><\/jats:bold>,<jats:italic><jats:bold>R<\/jats:bold><\/jats:italic>,<jats:italic><jats:bold>S<\/jats:bold><\/jats:italic><jats:bold>)<\/jats:bold>and<jats:bold>(<\/jats:bold><jats:italic><jats:bold>R<\/jats:bold><\/jats:italic>,<jats:italic><jats:bold>R<\/jats:bold><\/jats:italic>,<jats:italic><jats:bold>S<\/jats:bold><\/jats:italic><jats:bold>)<\/jats:bold>. The<jats:bold>(<\/jats:bold><jats:italic><jats:bold>R<\/jats:bold><\/jats:italic>,<jats:italic><jats:bold>R<\/jats:bold><\/jats:italic>,<jats:italic><jats:bold>S<\/jats:bold><\/jats:italic><jats:bold>)<\/jats:bold>stereoisomer was found in the crystal phase. It was revealed that the thiazine rings of equivalent benzothiazine fragments have different conformations, (a sofa or a half-chair). The two bicyclic fragments connected through the phenylmethylene group are oriented almost orthogonal to each other, subtending a dihedral angle of 82.16(7<jats:bold>)<\/jats:bold>\u00b0.<\/jats:p>","DOI":"10.1107\/s2056989023002505","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T09:23:17Z","timestamp":1679390597000},"page":"349-355","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":0,"title":["3,3\u2032-(Phenylmethylene)bis(1-ethyl-3,4-dihydro-1<i>H<\/i>-2,1-benzothiazine-2,2,4-trione): single-crystal X-ray diffraction study, quantum-chemical calculations and Hirshfeld surface analysis"],"prefix":"10.1107","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9032-6439","authenticated-orcid":true,"given":"Mariia O.","family":"Shyshkina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4505-3646","authenticated-orcid":true,"given":"Dmitry A.","family":"Lega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liudmyla M.","family":"Shemchuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina L.","family":"Starchikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0441-6479","authenticated-orcid":true,"given":"Leonid A.","family":"Shemchuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2023,3,21]]},"reference":[{"key":"ex2067_bb1","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.bioorg.2018.04.012","volume":"80","author":"Ahmad","year":"2018","journal-title":"Bioorg. 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