{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:22:21Z","timestamp":1785424941340,"version":"3.56.0"},"reference-count":20,"publisher":"International Union of Crystallography (IUCr)","issue":"5","license":[{"start":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T00:00:00Z","timestamp":1744070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T00:00:00Z","timestamp":1744070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"funder":[{"name":"Hacettepe University Scientific Research Project Unit","award":["013 D04 602 004"],"award-info":[{"award-number":["013 D04 602 004"]}]}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"accepted":{"date-parts":[[2025,4,3]]},"published-print":{"date-parts":[[2025,5,1]]},"abstract":"<jats:p>\n                    The title compound, C\n                    <jats:sub>21<\/jats:sub>\n                    H\n                    <jats:sub>18<\/jats:sub>\n                    N\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>4<\/jats:sub>\n                    , contains non-planar diazepine (in a boat\u2013sofa conformation) and pyran (envelope) rings. In the crystal, O\u2014H...O and N\u2014H...O hydrogen bonds link the molecules, enclosing\n                    <jats:italic>R<\/jats:italic>\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    (16) and\n                    <jats:italic>R<\/jats:italic>\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    (24) ring motifs, to generate [110] chains. Very weak \u03c0\u2013\u03c0 stacking interactions between the phenyl rings of adjacent molecules with an inter-centroid distance of 4.0264\u2005(9)\u2005\u00c5 help to consolidate a three-dimensional architecture. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions for the crystal packing are from H...H (45.1%), H...O\/O...H (23.2%) and H...C\/C...H (19.2%) interactions.\n                  <\/jats:p>","DOI":"10.1107\/s2056989025003032","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T03:27:07Z","timestamp":1743737227000},"page":"381-384","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":1,"title":["Synthesis and crystal structure of 2-(2,4-dioxo-6-methylpyran-3-ylidene)-4-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1\n                    <i>H<\/i>\n                    -1,5-benzodiazepine"],"prefix":"10.1107","volume":"81","author":[{"given":"Imane","family":"Faraj","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00r8w8f84","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lhoussaine","family":"El Ghayati","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00r8w8f84","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9857-4042","authenticated-orcid":true,"given":"Olivier","family":"Blacque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8602-4382","authenticated-orcid":true,"given":"Tuncer","family":"H\u00f6kelek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6945-1884","authenticated-orcid":true,"given":"Ahmed","family":"Mazzah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El Mokhtar","family":"Essassi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00r8w8f84","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6434-6093","authenticated-orcid":true,"given":"Nada Kheira","family":"Sebbar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2025,4,8]]},"reference":[{"key":"hb8131_bb1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/cbdd.12739","volume":"88","author":"An","year":"2016","journal-title":"Chem. Biol. Drug Des."},{"key":"hb8131_bb2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/BF01209549","volume":"10","author":"Boessenkool","year":"1980","journal-title":"J. Cryst. Mol. Struct."},{"key":"hb8131_bb4","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1107\/S0021889808042726","volume":"42","author":"Dolomanov","year":"2009","journal-title":"J. Appl. Cryst."},{"key":"hb8131_bb5","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/jhet.4167","volume":"58","author":"El Ghayati","year":"2021","journal-title":"J. Heterocycl. Chem."},{"key":"hb8131_bb6","doi-asserted-by":"crossref","unstructured":"Essaghouani, A., Boulhaoua, M., El Hafi, M., Benchidmi, M., Essassi, E. M. & Mague, J. T. (2017). IUCrData, 2, x170120.","DOI":"10.1107\/S2414314617000323"},{"key":"hb8131_bb7","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1107\/S0108768189012929","volume":"46","author":"Etter","year":"1990","journal-title":"Acta Cryst. B"},{"key":"hb8131_bb8","doi-asserted-by":"crossref","first-page":"502","DOI":"10.3184\/174751915X14396478950860","volume":"39","author":"Faidallah","year":"2015","journal-title":"J. Chem. Res."},{"key":"hb8131_bb9","doi-asserted-by":"crossref","first-page":"105331","DOI":"10.1016\/j.bioorg.2021.105331","volume":"117","author":"Gawandi","year":"2021","journal-title":"Bioorg. Chem."},{"key":"hb8131_bb10","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1107\/S2052520616003954","volume":"72","author":"Groom","year":"2016","journal-title":"Acta Cryst. B"},{"key":"hb8131_bb11","first-page":"81","volume":"4","author":"Jyoti","year":"2013","journal-title":"Pharm. Sin."},{"key":"hb8131_bb12","doi-asserted-by":"crossref","first-page":"3814","DOI":"10.1039\/b704980c","author":"McKinnon","year":"2007","journal-title":"Chem. Commun."},{"key":"hb8131_bb21","doi-asserted-by":"crossref","first-page":"4264","DOI":"10.1016\/j.tetlet.2013.05.148","volume":"54","author":"Lal","year":"2013","journal-title":"Tetrahedron Lett."},{"key":"hb8131_bb13","unstructured":"Rigaku OD (2024). CrysAlis PRO. Rigaku Oxford Diffraction, Yarnton, England."},{"key":"hb8131_bb14","first-page":"925","volume":"6","author":"Sharma","year":"2017","journal-title":"World J. Pharm. Res."},{"key":"hb8131_bb15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053273314026370","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Cryst. A"},{"key":"hb8131_bb16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053229614024218","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Cryst. C"},{"key":"hb8131_bb17","doi-asserted-by":"crossref","first-page":"4639","DOI":"10.1039\/D0NA00491J","volume":"2","author":"Siddiqui","year":"2020","journal-title":"Nanoscale Adv."},{"key":"hb8131_bb18","first-page":"143","volume":"27","author":"Singh","year":"2017","journal-title":"Indian J. Heterocycl. Chem."},{"key":"hb8131_bb19","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1107\/S1600576721002910","volume":"54","author":"Spackman","year":"2021","journal-title":"J. Appl. Cryst."},{"key":"hb8131_bb20","doi-asserted-by":"crossref","first-page":"10428","DOI":"10.1039\/C9NJ06332C","volume":"44","author":"Wu","year":"2020","journal-title":"New J. Chem."}],"container-title":["Acta Crystallographica Section E Crystallographic Communications"],"original-title":[],"link":[{"URL":"https:\/\/journals.iucr.org\/e\/issues\/2025\/05\/00\/hb8131\/hb8131.pdf","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.iucr.org\/e\/issues\/2025\/05\/00\/hb8131\/hb8131.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T11:51:21Z","timestamp":1746532281000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.iucr.org\/paper?S2056989025003032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,8]]},"references-count":20,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,5]]}},"alternative-id":["S2056989025003032"],"URL":"https:\/\/doi.org\/10.1107\/s2056989025003032","relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.1107\/S2056989025003032\/hb8131sup1.cif","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989025003032\/hb8131Isup4.cdx","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989025003032\/hb8131Isup5.cml","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989025003032\/hb8131Isup5.hkl","asserted-by":"subject"},{"id-type":"doi","id":"10.1107\/S2056989025003032\/hb8131sup3.txt","asserted-by":"subject"}]},"ISSN":["2056-9890"],"issn-type":[{"value":"2056-9890","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,8]]},"assertion":[{"value":"Acta Crystallographica Section E: Crystallographic Communications","order":0,"name":"journal","label":"Publication","explanation":{"URL":"https:\/\/journals.iucr.org\/e"},"group":{"name":"general","label":"General"}},{"value":"research communications","order":1,"name":"content_type","label":"Content type","explanation":{"URL":"https:\/\/journals.iucr.org\/e\/services\/notesforauthors.html"},"group":{"name":"general","label":"General"}},{"value":"Available","URL":"https:\/\/scripts.iucr.org\/cgi-bin\/citedin?hb8131","order":2,"name":"article_metrics","label":"Article metrics","group":{"name":"general","label":"General"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"27 March 2025","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication history"}},{"value":"3 April 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication history"}},{"value":"8 April 2025","order":2,"name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication history"}},{"value":"This article has supporting information","name":"supplementary_materials","label":"Supplementary materials","explanation":{"URL":"https:\/\/scripts.iucr.org\/cgi-bin\/sendsup?hb8131"}},{"value":"\u00a9 2025 Faraj\n                      et al.","order":0,"name":"copyright","label":"Copyright","explanation":{"URL":"https:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}},{"value":"Creative Commons Attribution (CC-BY)","order":1,"name":"license","label":"Licence","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}}]}}