{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:16:11Z","timestamp":1785435371906,"version":"3.56.0"},"reference-count":35,"publisher":"International Union of Crystallography (IUCr)","issue":"12","license":[{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"accepted":{"date-parts":[[2025,11,12]]},"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:p>\n                    The crystal structures of two new tinidazole {1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1\n                    <jats:italic>H<\/jats:italic>\n                    -imidazole, TNZ, C\n                    <jats:sub>8<\/jats:sub>\n                    H\n                    <jats:sub>13<\/jats:sub>\n                    N\n                    <jats:sub>3<\/jats:sub>\n                    O\n                    <jats:sub>4<\/jats:sub>\n                    S} forms, triclinic and hemihydrate, have been determined and compared to that of the known monoclinic form. The triclinic and hemihydrate structures each contain two independent molecules with similar conformations, whereas the monoclinic form adopts a distinct geometry. The conformational differences arise mainly from variations in the N\u2014C\u2014C\u2014S torsion angle. A conformational study confirmed two preferred types of molecular conformations characteristic of tinidazole polymorphs. Interaction-energy analysis indicates that, despite differences in the crystal packing of the monoclinic and triclinic polymorphs, dispersion forces play a major role in consolidation of their structures.\n                  <\/jats:p>","DOI":"10.1107\/s2056989025010126","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T07:55:08Z","timestamp":1763366108000},"page":"1170-1177","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":0,"title":["Crystal structures and conformational features of new forms of tinidazole"],"prefix":"10.1107","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-9970-1404","authenticated-orcid":true,"given":"Valeryia","family":"Hushcha","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05cq64r17","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4150-0506","authenticated-orcid":true,"given":"Justyna","family":"Dominikowska","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05cq64r17","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3546-920X","authenticated-orcid":true,"given":"Lilianna","family":"Ch\u0119ci\u0144ska","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05cq64r17","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2025,11,21]]},"reference":[{"key":"vm2319_bb1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.poly.2013.09.030","volume":"67","author":"Alfaro-Fuentes","year":"2014","journal-title":"Polyhedron"},{"key":"vm2319_bb2","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1107\/S0108768110012048","volume":"66","author":"Allen","year":"2010","journal-title":"Acta Cryst. 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