{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:19:46Z","timestamp":1785428386226,"version":"3.56.0"},"reference-count":25,"publisher":"International Union of Crystallography (IUCr)","issue":"2","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr E Cryst Commun","Acta Cryst E","Acta Cryst Sect E","Acta Crystallogr E","Acta Crystallogr Sect E","Acta Cryst E Cryst Commun","Acta Cryst Sect E Cryst Commun"],"accepted":{"date-parts":[[2026,1,6]]},"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:p>\n                    In the crystal structure of the title compound, C\n                    <jats:sub>22<\/jats:sub>\n                    H\n                    <jats:sub>24<\/jats:sub>\n                    ClNO\n                    <jats:sub>2<\/jats:sub>\n                    , the piperidine ring adopts a boat conformation. Intra- and intermolecular C\u2014H...Cl hydrogen bonds are observed. The intermolecular interactions were quantified and analysed using Hirshfeld surface analysis, revealing that H...H interactions contribute most to the crystal packing (56.1%).\n                  <\/jats:p>","DOI":"10.1107\/s2056989026000083","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T07:24:49Z","timestamp":1767770689000},"page":"152-155","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":0,"title":["Crystal structure and Hirshfeld surface analysis of 1-(2-chloroacetyl)-3-methyl-2,6-bis(4-methylphenyl)piperidin-4-one"],"prefix":"10.1107","volume":"82","author":[{"given":"Sivagnanam","family":"Divyabharathi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnan","family":"Rajeswari","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01x24z140","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thankakan","family":"Vidhyasagar","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01x24z140","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivashanmugam","family":"Selvanayagam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2026,1,8]]},"reference":[{"key":"tx2106_bb1","doi-asserted-by":"crossref","first-page":"6542","DOI":"10.1016\/j.bmcl.2008.10.045","volume":"18","author":"Aridoss","year":"2008","journal-title":"Bioorg. 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