{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:08:23Z","timestamp":1791259703254,"version":"4.1.0"},"reference-count":26,"publisher":"International Union of Crystallography (IUCr)","issue":"4","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"funder":[{"DOI":"10.13039\/100005926","name":"International Centre for Diffraction Data","doi-asserted-by":"crossref","award":["09-03"],"award-info":[{"award-number":["09-03"]}],"id":[{"id":"10.13039\/100005926","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["IUCrData","IUCr Data","International Union Crystallogr Data","Int Union Cryst Data"],"accepted":{"date-parts":[[2026,4,21]]},"published-print":{"date-parts":[[2026,4,28]]},"abstract":"<jats:p>\n                    The crystal structure of bepotastine besylate {systematic name: 1-(3-carboxypropyl)-4-[(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidin-1-ium benzenesulfonate, C\n                    <jats:sub>21<\/jats:sub>\n                    H\n                    <jats:sub>26<\/jats:sub>\n                    ClN\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>+<\/jats:sup>\n                    \u00b7C\n                    <jats:sub>6<\/jats:sub>\n                    H\n                    <jats:sub>5<\/jats:sub>\n                    O\n                    <jats:sub>3<\/jats:sub>\n                    S\n                    <jats:sup>\u2212<\/jats:sup>\n                    ) was refined using synchrotron X-ray powder diffraction data, and optimized using density functional theory techniques. Bepotastine besylate crystallizes in the space group\n                    <jats:italic>P<\/jats:italic>\n                    1, with\n                    <jats:italic>a<\/jats:italic>\n                    \u00a0= 8.0153\u2005(6),\n                    <jats:italic>b<\/jats:italic>\n                    \u00a0= 9.8211\u2005(5),\n                    <jats:italic>c<\/jats:italic>\n                    \u00a0= 10.2345\u2005(10)\u2005\u00c5, \u03b1\u00a0= 88.164\u2005(2), \u03b2\u00a0= 68.962\u2005(2), \u03b3\u00a0= 65.8917\u2005(8)\u00b0,\n                    <jats:italic>V<\/jats:italic>\n                    \u00a0= 680.149\u2005(1)\u2005\u00c5\n                    <jats:sup>3<\/jats:sup>\n                    and\n                    <jats:italic>Z<\/jats:italic>\n                    \u00a0= 1 at 298\u2005K. N\u2014H...O and O\u2014H...O hydrogen bonds link the cations and anions into a chain extending parallel to the\n                    <jats:italic>c<\/jats:italic>\n                    axis, with a graph set\n                    <jats:italic>C<\/jats:italic>\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    (11).\n                  <\/jats:p>","DOI":"10.1107\/s2414314626004244","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:27:16Z","timestamp":1777458436000},"update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":1,"title":["Bepostastine besylate"],"prefix":"10.1107","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6586-2944","authenticated-orcid":true,"given":"Jacob K.","family":"Salazar","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02ehan050","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6610-541X","authenticated-orcid":true,"given":"James A.","family":"Kaduk","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02ehan050","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Dosen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9506-7237","authenticated-orcid":true,"given":"Thomas N.","family":"Blanton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"zl4094_bb1","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1107\/S0021889813013113","volume":"46","author":"Altomare","year":"2013","journal-title":"J. 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