{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:00:24Z","timestamp":1761058824891,"version":"3.41.2"},"reference-count":7,"publisher":"Emerald","issue":"4","license":[{"start":{"date-parts":[[2008,6,20]],"date-time":"2008-06-20T00:00:00Z","timestamp":1213920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.emerald.com\/insight\/site-policies"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,6,20]]},"abstract":"<jats:sec><jats:title content-type=\"abstract-heading\">Purpose<\/jats:title><jats:p>The purpose of this paper is to present a novel microbiological lab robot that facilitates high through\u2010put sample preparation for rapid state\u2010of\u2010the\u2010art identification.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Design\/methodology\/approach<\/jats:title><jats:p>Development concentrated on two main points: research initially focused on various methods for picking a micro\u2010organism colony from a petri dish without any medium adhering; and subsequently on completely documenting sample handling with little effort.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Findings<\/jats:title><jats:p>A sensorless system for picking micro\u2010organisms from a petri dish was engineered and prototyped. A documented process in the demonstrator demonstrates its usability even for certified clinical operations.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Research limitations\/implications<\/jats:title><jats:p>The handling of solid phase biological objects is only in its infancy. This research focused on the preparation of samples from micro\u2010organism colonies for MALDI\u2010TOF MS. A specific type of gripper was developed to do this. The handling of other biological objects, e.g. from cell cultures or intermediate stages of tissue engineering, is still a largely open field for future research.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Practical implications<\/jats:title><jats:p>New analysis methods often only become accepted when the preparatory processes are also taken into account \u2013 highly parallel operations (e.g. MALDI\u2010TOF MS) are particularly impractical for humans and difficult for data handling to manage. Given the specific demands, only an interdisciplinary team can adapt the automation engineering successfully.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Originality\/value<\/jats:title><jats:p>This paper presents an approach to and implementation of the automation of manual operations in biotechnology. It is intended to encourage health professionals, biologists and engineers to jointly research and interdisciplinarily automate complex operations.<\/jats:p><\/jats:sec>","DOI":"10.1108\/01439910810876409","type":"journal-article","created":{"date-parts":[[2008,6,28]],"date-time":"2008-06-28T07:01:36Z","timestamp":1214636496000},"page":"311-315","source":"Crossref","is-referenced-by-count":3,"title":["MIROB: automatic rapid identification of micro\u2010organisms in high through\u2010put"],"prefix":"10.1108","volume":"35","author":[{"given":"Oliver","family":"Lange","sequence":"first","affiliation":[]},{"given":"Marcel","family":"Erhard","sequence":"additional","affiliation":[]},{"given":"Christian","family":"Teutsch","sequence":"additional","affiliation":[]},{"given":"Joerg","family":"Sander","sequence":"additional","affiliation":[]}],"member":"140","reference":[{"key":"key2022021920354445200_b2","doi-asserted-by":"crossref","unstructured":"Al Dahouk, S., Noeckler, K., Scholz, H.C., Tomaso, H., Bogumil, R. and Neubauer, H. 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(2005), \u201cEight new species of the genus Micromonospora, Micromonospora citrea sp. nov., Micromonospora echinaurantiaca sp. nov., Micromonospora echinofusca sp. nov. Micromonospora fulviviridis sp. nov., Micromonospora inyonensis sp. nov., Micromonospora peucetia sp. nov., Micromonospora sagamiensis sp. nov., and Micromonospora viridifaciens sp. nov.\u201d, Systematic and Applied Microbiology, Vol. 28 No. 4, pp. 328\u201039.","DOI":"10.1016\/j.syapm.2004.12.011"},{"key":"key2022021920354445200_b3","doi-asserted-by":"crossref","unstructured":"Schmidt, O. and Kallow, W. (2005), \u201cDifferentiation of indoor wood decay by fungi with MALDI\u2010TOF mass spectrometry\u201d, Holzforschung, Vol. 59, pp. 374\u20107.","DOI":"10.1515\/HF.2005.062"},{"key":"key2022021920354445200_b6","unstructured":"Schmucker, U., Lange, O., B\u00f6hme, T., Erhard, M. and Hauptmann, P. (2004), \u201cVerfahren und Vorrichtung zur Aufnahme von Zellmaterial und Ablage desselben\u201d, Deutsches Patent (pending) DE102004020885."},{"key":"key2022021920354445200_b1","doi-asserted-by":"crossref","unstructured":"Stackebrandt, E., P\u00e4uker, O. and Erhard, M. (2005), \u201cIdentifying myxococci (Corallococcus) strains by matrix assisted laser desorption ionization time\u2010of\u2010flight (MALDI TOF) mass spectrometry and comparison with gene sequence phylogenies\u201d, Current Microbiology, Vol. 50 No. 2, pp. 71\u20107.","DOI":"10.1007\/s00284-004-4395-3"},{"key":"key2022021920354445200_b7","doi-asserted-by":"crossref","unstructured":"Teutsch, C., Berndt, D., Trostmann, E. and Weber, M. (2006), \u201cReal\u2010time detection of elliptic shapes for automated object recognition and object tracking\u201d, Proceedings of Machine Vision Applications in Industrial Inspection XIV. 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