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Supported on these case studies and literature, this paper presents guidelines to planning, conducting and analysis involving technical and organizational aspects.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Findings<\/jats:title><jats:p>Solving problems in industry, including in companies recognized as competent in the respective industrial sector, is not just a question of applying the right technique. Ceramic industry case study illustrates how important are non\u2010statistical issues in DOE application. Paint industry case study illustrates the strong relationship of the results with incorporating presented guidelines into practice. Moreover, both case studies consolidating a fundamental advantage of DOE: experimentation provides more knowledge about products, processes and technologies, even in unsuccessful case studies.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Research limitations\/implications<\/jats:title><jats:p>Unsuccessful cases studies are very useful for identifying pitfalls and others limitations. This paper highlight difficulties aroused from non\u2010statistical aspects, although it is possible to find unsuccessful case studies due to statistical issues also. So, papers illustrating inadequate application of statistical techniques are welcome.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Practical implications<\/jats:title><jats:p>Successful DOE implementation depends on statistical and non\u2010statistical aspects. Although none of them shall be neglected, technical skills and technological knowledge about processes and products, management understanding of potential possibilities of statistical techniques and statistical fundamentals and knowledge about techniques of DOE must be ensuring to successful case studies in industrial setting.<\/jats:p><\/jats:sec><jats:sec><jats:title content-type=\"abstract-heading\">Originality\/value<\/jats:title><jats:p>This paper highlights non\u2010statistical aspects instead of the statistical ones. Tob overcome difficulties structured guidelines were designed to support DOE application in industrial setting.<\/jats:p><\/jats:sec>","DOI":"10.1108\/09544780610671057","type":"journal-article","created":{"date-parts":[[2006,7,4]],"date-time":"2006-07-04T07:42:57Z","timestamp":1151998977000},"page":"386-399","source":"Crossref","is-referenced-by-count":23,"title":["Guidelines to help practitioners of design of experiments"],"prefix":"10.1108","volume":"18","author":[{"given":"Nuno R.P.","family":"Costa","sequence":"first","affiliation":[]},{"given":"Ant\u00f3nio R.","family":"Pires","sequence":"additional","affiliation":[]},{"given":"Celma O.","family":"Ribeiro","sequence":"additional","affiliation":[]}],"member":"140","reference":[{"key":"key2022013019452400800_b1","doi-asserted-by":"crossref","unstructured":"Adebanjo, D. and Kehoe, D. 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