{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T19:01:28Z","timestamp":1770577288385,"version":"3.49.0"},"reference-count":22,"publisher":"IEEE","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1109\/bibe.2012.6399686","type":"proceedings-article","created":{"date-parts":[[2013,1,7]],"date-time":"2013-01-07T16:34:59Z","timestamp":1357576499000},"page":"266-269","source":"Crossref","is-referenced-by-count":2,"title":["Enhancing the effectiveness of virtual screening by using the ChemBioServer: Application to the discovery of PI3Kα inhibitors"],"prefix":"10.1109","author":[{"given":"Paraskevi","family":"Gkeka","sequence":"first","affiliation":[]},{"given":"Emmanouil","family":"Athanasiadis","sequence":"additional","affiliation":[]},{"given":"George","family":"Spyrou","sequence":"additional","affiliation":[]},{"given":"Zoe","family":"Cournia","sequence":"additional","affiliation":[]}],"member":"263","reference":[{"key":"19","year":"2011","journal-title":"Glide"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1063\/1.470648"},{"key":"22","author":"kerns","year":"2008","journal-title":"Drug-like Properties Concepts Structure Design and Methods From ADME to Toxicity Optimization"},{"key":"18","year":"2011","journal-title":"SiteMap"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.540130805"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1063\/1.464397"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1063\/1.445869"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9991(77)90098-5"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1021\/jp973084f"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.105.078154"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1021\/jm051256o"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.2174\/156802609789207127"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1021\/jm0306430"},{"key":"2","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/nature03197","article-title":"Virtual screening of chemical libraries","volume":"432","author":"shoichet","year":"2004","journal-title":"Nature"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20289"},{"key":"1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2926"},{"key":"7","article-title":"ChemBank: A small-molecule screening and cheminformatics resource database","volume":"36","author":"seiler","year":"2008","journal-title":"Nucleic Acids Research"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2010.10.003"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1021\/ci049714+"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1021\/jm801100v"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1993.1626"},{"key":"8","doi-asserted-by":"crossref","DOI":"10.1093\/bioinformatics\/bts551","article-title":"ChemBioServer: A webbased pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery","author":"athanasiadis","year":"2012","journal-title":"Bioinformatics"}],"event":{"name":"2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)","location":"Larnaca, Cyprus","start":{"date-parts":[[2012,11,11]]},"end":{"date-parts":[[2012,11,13]]}},"container-title":["2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx5\/6387371\/6399636\/06399686.pdf?arnumber=6399686","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T01:18:35Z","timestamp":1498007915000},"score":1,"resource":{"primary":{"URL":"http:\/\/ieeexplore.ieee.org\/document\/6399686\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":22,"URL":"https:\/\/doi.org\/10.1109\/bibe.2012.6399686","relation":{},"subject":[],"published":{"date-parts":[[2012,11]]}}}