{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T19:01:45Z","timestamp":1754161305013,"version":"3.41.2"},"reference-count":13,"publisher":"IEEE","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1109\/bibm47256.2019.8982978","type":"proceedings-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T02:49:51Z","timestamp":1581043791000},"page":"2157-2162","source":"Crossref","is-referenced-by-count":0,"title":["A MapReduce tool for in-depth analysis of KEGG pathways: identification and visualization of therapeutic target candidates"],"prefix":"10.1109","author":[{"given":"Giuseppe Alessandro Parasiliti","family":"Palumbo","sequence":"first","affiliation":[{"name":"University of Catania,Department of Mathematics and Computer Science,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Biondi","sequence":"additional","affiliation":[{"name":"University of Catania,Department of Mathematics and Computer Science,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Sgroi","sequence":"additional","affiliation":[{"name":"University of Catania,Department of Mathematics and Computer Science,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marzio","family":"Pennisi","sequence":"additional","affiliation":[{"name":"University of Catania,Department of Mathematics and Computer Science,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Russo","sequence":"additional","affiliation":[{"name":"University of Catania,Department of Drug Sciences,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Pappalardo","sequence":"additional","affiliation":[{"name":"University of Catania,Department of Drug Sciences,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"doi-asserted-by":"publisher","key":"ref10","DOI":"10.1093\/bioinformatics\/btw332"},{"doi-asserted-by":"publisher","key":"ref11","DOI":"10.1093\/nar\/gku1003"},{"doi-asserted-by":"publisher","key":"ref12","DOI":"10.1093\/bioinformatics\/btt740"},{"year":"2018","author":"wang","journal-title":"Phospho-erk is a response biomarker to a combination of sorafenib and mek inhibition in liver cancer","key":"ref13"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1093\/bioinformatics\/btv557"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.1109\/TVCG.2011.185"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.1038\/nature09627"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.1093\/bioinformatics\/bty969"},{"year":"0","journal-title":"mrjob webpage","key":"ref8"},{"doi-asserted-by":"publisher","key":"ref7","DOI":"10.1093\/nar\/28.1.27"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"393","DOI":"10.18632\/genesandcancer.41","article-title":"mtorc2 modulates feedback regulation of p38 mapk activity via dusp10\/mkp5 to confer differential responses to pp 242 in glioblastoma","volume":"5","author":"benavides-serrato","year":"2014","journal-title":"Genes &amp; Cancer"},{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.1186\/1476-4598-13-108"},{"doi-asserted-by":"publisher","key":"ref9","DOI":"10.1109\/EMPDP.2019.8671609"}],"event":{"name":"2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","start":{"date-parts":[[2019,11,18]]},"location":"San Diego, CA, USA","end":{"date-parts":[[2019,11,21]]}},"container-title":["2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/8965270\/8982928\/08982978.pdf?arnumber=8982978","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T19:40:50Z","timestamp":1753731650000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/8982978\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":13,"URL":"https:\/\/doi.org\/10.1109\/bibm47256.2019.8982978","relation":{},"subject":[],"published":{"date-parts":[[2019,11]]}}}