{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T18:08:59Z","timestamp":1765994939191,"version":"3.37.3"},"reference-count":29,"publisher":"IEEE","license":[{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006190","name":"Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,12,9]]},"DOI":"10.1109\/bibm52615.2021.9669509","type":"proceedings-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T20:40:30Z","timestamp":1642192830000},"page":"456-461","source":"Crossref","is-referenced-by-count":8,"title":["TopoPhy-CNN: Integrating Topological Information of Phylogenetic Tree for Host Phenotype Prediction From Metagenomic Data"],"prefix":"10.1109","author":[{"given":"Bojing","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duo","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingpeng","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"ref10","article-title":"The gut microbiota as an environmental factor that regulates fat storage","volume":"101","author":"fredrik","year":"2004","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref11","article-title":"Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures","volume":"116","author":"iradj","year":"2019","journal-title":"Proceedings of the National Academy of Sciences"},{"journal-title":"Metagenomics of the Human Body","year":"2011","author":"karen","key":"ref12"},{"key":"ref13","article-title":"A reliable method for colorectal cancer prediction based on feature selection and support vector machine","volume":"57","author":"dandan","year":"2019","journal-title":"Medical & Biological Engineering & Computing"},{"key":"ref14","article-title":"Gene selection and classification of microarray data using random forest","volume":"7","author":"ram\u00f3n","year":"2006","journal-title":"BioMed Central"},{"key":"ref15","article-title":"Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights","volume":"12","author":"edoardo","year":"2016","journal-title":"PLoS Computational Biology"},{"key":"ref16","article-title":"Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome","volume":"141","author":"delphine","year":"2011","journal-title":"Gastroenterology"},{"key":"ref17","first-page":"603","article-title":"Deep Learning Techniques on Text Classification Using Natural Language Processing (NLP) In Social Healthcare Network: A Comprehensive Survey","author":"p","year":"2021","journal-title":"2021 3rd International Conference on Signal Processing and Communication (ICPSC)"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.4236\/jcc.2021.93002"},{"key":"ref19","first-page":"64","article-title":"Identifying viruses from metagenomic data using deep learning","author":"jie","year":"2020","journal-title":"Quantitative Biology"},{"key":"ref28","article-title":"Comparison of the predicted and observed secondary structure of T4 phage lysozyme","volume":"405","author":"matthews","year":"1975","journal-title":"Biochimica et Biophysica Acta"},{"key":"ref4","article-title":"Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite of Clostridia spp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia","volume":"13","year":"2010","journal-title":"Nutritional Neuroscience"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3589"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.11.5721-5732.2005"},{"key":"ref6","article-title":"Lipids from heterotrophic microbes: advances in metabolism research","volume":"29","author":"matyas","year":"2010","journal-title":"Trends in Biotechnology"},{"key":"ref29","article-title":"Ten quick tips for machine learning in computational biology","volume":"10","author":"davide","year":"2017","journal-title":"BioData Mining"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2017.157"},{"key":"ref8","article-title":"Microbes and mental health: A review","volume":"66","author":"ryan","year":"2017","journal-title":"Brain Behavior and Immunity"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-06-11-0179"},{"key":"ref2","article-title":"Meta-analyses of human gut microbes associated with obesity and IBD","volume":"588","author":"william","year":"2014","journal-title":"FEBS Letters"},{"key":"ref1","doi-asserted-by":"crossref","DOI":"10.1038\/nature08821","article-title":"A human gut microbial gene catalogue established by metagenomic sequencing","volume":"464","author":"qin","year":"2010","journal-title":"Nature"},{"key":"ref9","article-title":"Human Intestinal Lumen and Mucosa-Associated Microbiota in Patients with Colorectal Cancer","volume":"7","author":"weiguang","year":"2012","journal-title":"PLoS ONE"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1162\/neco.1989.1.4.541","article-title":"Backpropagation Applied to Handwritten Zip Code Recognition","volume":"1","author":"l y","year":"1989","journal-title":"Neural Computation"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/nargab\/lqaa009"},{"key":"ref21","article-title":"CNN-MGP: Convolutional Neural Networks for Metagenomics Gene Prediction","volume":"11","author":"amani","year":"2019","journal-title":"Interdisciplinary Sciences Computational Life Sciences"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2148-6-1"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1109\/JBHI.2020.2993761"},{"key":"ref26","article-title":"Adam: A Method for Stochastic Optimization","author":"kingma","year":"2014","journal-title":"Computer Science"},{"key":"ref25","first-page":"594","article-title":"Patrocladistic classification","author":"stuessy","year":"2008","journal-title":"Taxon"}],"event":{"name":"2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","start":{"date-parts":[[2021,12,9]]},"location":"Houston, TX, USA","end":{"date-parts":[[2021,12,12]]}},"container-title":["2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/9669261\/9669139\/09669509.pdf?arnumber=9669509","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T16:57:10Z","timestamp":1652201830000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/9669509\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,9]]},"references-count":29,"URL":"https:\/\/doi.org\/10.1109\/bibm52615.2021.9669509","relation":{},"subject":[],"published":{"date-parts":[[2021,12,9]]}}}