{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T21:45:24Z","timestamp":1770846324025,"version":"3.50.1"},"reference-count":43,"publisher":"IEEE","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AG068002"],"award-info":[{"award-number":["R01AG068002"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,15]]},"DOI":"10.1109\/bibm66473.2025.11356803","type":"proceedings-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T21:19:40Z","timestamp":1769721580000},"page":"7673-7680","source":"Crossref","is-referenced-by-count":0,"title":["RaiLED-AD: Rationale-Guided Knowledge Transfer for Alzheimer's Disease Prediction From Electronic Health Records"],"prefix":"10.1109","author":[{"given":"Shijia","family":"Zhang","sequence":"first","affiliation":[{"name":"Johns Hopkins University,Dept. of Biomedical Informatics & Data Science,Baltimore,USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Johns Hopkins University,Dept. of Biostatistics,Baltimore,USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadi","family":"Kharrazi","sequence":"additional","affiliation":[{"name":"Johns Hopkins University,Dept. of Health Policy and Management,Baltimore,USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.13016"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2022.101580"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.003"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/WAD.0b013e3181a6bebc"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2023.107356"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-024-00573-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-020-0256-0"},{"key":"ref8","journal-title":"Early prediction of alzheimer\u2019s disease and related d ementias using realworld electronic health records - li - 2023 - alzheimer\u2019s & dementia wiley online library"},{"key":"ref9","volume-title":"Publicly available clinical bert embeddings","author":"Alsentzer","year":"2019"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2023.104442"},{"key":"ref11","doi-asserted-by":"crossref","DOI":"10.18653\/v1\/2021.wnut-1.37","volume-title":"Robustness and sensitivity of bert models predicting alzheimer\u2019s disease from text","author":"Novikova","year":"2021"},{"key":"ref12","volume-title":"Cehr-bert: Incorporating temporal information from structured ehr data to improve prediction tasks","author":"Pang","year":"2021"},{"key":"ref13","volume-title":"Ehrshot: An ehr benchmark for few-shot evaluation of foundation models","author":"Wornow","year":"2023"},{"key":"ref14","volume-title":"Large language models are clinical reasoners: Reasoning-aware diagnosis framework with prompt-generated rationales","author":"Kwon","year":"2024"},{"key":"ref15","doi-asserted-by":"crossref","DOI":"10.1038\/s41746-024-01366-4","volume-title":"Probabilistic medical predictions of large language models","author":"Gu","year":"2024"},{"key":"ref16","volume-title":"Distilling the knowledge in a neural network","author":"Hinton","year":"2015"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1109\/access.2020.3031549"},{"key":"ref18","volume-title":"Contrastive representation distillation","author":"Tian","year":"2022"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-75331-2"},{"issue":"PMLR","key":"ref20","first-page":"54156","article-title":"Contrastive learning for clinical outcome prediction with partial data sources","volume-title":"Proceedings of Machine Learning Research (PMLR)","volume":"235","author":"Xia","year":"2024"},{"key":"ref21","volume-title":"Ckd-ehr:clinical knowledge distillation for electronic health records","author":"Wang","year":"2025"},{"key":"ref22","volume-title":"Mind: Modality-informed knowledge distillation framework for multimodal clinical prediction tasks","author":"Guerra-Manzanares","year":"2025"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-025-01646-7"},{"key":"ref24","volume-title":"Billing codes for alzheimer\u2019s and related dementia"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12199"},{"key":"ref26","volume-title":"Towards expert-level medical question answering with large language models","author":"Singhal","year":"2023"},{"issue":"1","key":"ref27","first-page":"1","volume":"3","author":"Gu","journal-title":"Domain-specific language model pretraining for biomedical natural language processing"},{"key":"ref28","volume-title":"Representation learning with contrastive predictive coding","author":"van den Oord","year":"2019"},{"key":"ref29","volume-title":"Supervised contrastive learning","author":"Khosla","year":"2021"},{"key":"ref30","volume-title":"LoRA: Low-rank adaptation of large language models.","author":"Hu"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1145\/2939672.2939785"},{"key":"ref32","volume-title":"Bert: Pre-training of deep bidirectional transformers for language understanding","author":"Devlin","year":"2019"},{"key":"ref33","author":"He","year":"2023","journal-title":"Debertav3: Improving deberta using electra-style pre-training with gradient-disentangled embedding sharing"},{"key":"ref34","doi-asserted-by":"crossref","DOI":"10.18653\/v1\/D19-5602","volume-title":"Hello, it\u2019s gpt-2 - how can i help you? towards the use of pretrained language models for task-oriented dialogue systems","author":"Budzianowski","year":"2019"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.18653\/v1\/2020.acl-main.740"},{"key":"ref36","author":"Yu","year":"2025","journal-title":"Finemedlm-o1: Enhancing medical knowledge reasoning ability of 11 m from supervised fine-tuning to test-time training"},{"key":"ref37","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-52417-z","volume-title":"Towards building multilingual language model for medicine","author":"Qiu","year":"2024"},{"key":"ref38","author":"DeepSeek-AI","year":"2025","journal-title":"Deepseek-r1: Incentivizing reasoning capability in llms via reinforcement learning"},{"key":"ref39","volume-title":"Qwen3 technical report","author":"Team","year":"2025"},{"key":"ref40","volume-title":"Palmyra-Med-70b: A powerful LLM designed for healthcare","author":"Team","year":"2024"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1002\/dad2.12186"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g5205"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-180745"}],"event":{"name":"2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","location":"Wuhan, China","start":{"date-parts":[[2025,12,15]]},"end":{"date-parts":[[2025,12,18]]}},"container-title":["2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx8\/11355913\/11355975\/11356803.pdf?arnumber=11356803","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T20:53:10Z","timestamp":1770843190000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/11356803\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,15]]},"references-count":43,"URL":"https:\/\/doi.org\/10.1109\/bibm66473.2025.11356803","relation":{},"subject":[],"published":{"date-parts":[[2025,12,15]]}}}