{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T16:12:14Z","timestamp":1755792734486,"version":"3.44.0"},"reference-count":23,"publisher":"IEEE","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1109\/embc.2016.7590979","type":"proceedings-article","created":{"date-parts":[[2016,10,20]],"date-time":"2016-10-20T16:57:43Z","timestamp":1476982663000},"page":"1439-1442","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of multidrug cancer chronotherapy based on cell cycle model under influences of circadian clock"],"prefix":"10.1109","author":[{"given":"Hiroshi","family":"Inokawa","sequence":"first","affiliation":[{"name":"Biomodeling Lab, Graduate School of Information Sciences, Tohoku University, Sendai, 980-8579 Japan"}]},{"given":"Norihiro","family":"Katayama","sequence":"additional","affiliation":[{"name":"Biomodeling Lab, Graduate School of Information Sciences, Tohoku University, Sendai, 980-8579 Japan"}]},{"given":"Mitsuyuki","family":"Nakao","sequence":"additional","affiliation":[{"name":"Biomodeling Lab, Graduate School of Information Sciences, Tohoku University, Sendai, 980-8579 Japan"}]}],"member":"263","reference":[{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.07.001"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.matcom.2012.03.005"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1098\/rsfs.2010.0009"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2010.03.017"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0904837106"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.01.047"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800780120"},{"journal-title":"Partial Differential Equations for Scientists and Engineers","year":"1982","author":"farlow","key":"ref17"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511781452.007"},{"key":"ref19","first-page":"3039","article-title":"Transport of molecules in the tumor interstitium: A review","volume":"47","author":"jain","year":"1987","journal-title":"Cancer Res"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1182\/blood.V77.12.2603.2603","article-title":"DNA synthesis in human bone marrow is circadian stage dependent","volume":"77","author":"smaaland","year":"1991","journal-title":"Blood"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3444"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4161\/cc.9.6.11046"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64135-1"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2006.11.001"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-004-6603-z"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4161\/cc.8.6.7869"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000712"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1021\/cr980421n"},{"year":"0","key":"ref22","article-title":"5-Fluorouracil: Product Information Sheet"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/90.19.1480"},{"year":"0","key":"ref23","article-title":"cis-Diamineplatinum(II) dichloride crystalline : Product Information Sheet"}],"event":{"name":"2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","start":{"date-parts":[[2016,8,16]]},"location":"Orlando, FL, USA","end":{"date-parts":[[2016,8,20]]}},"container-title":["2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/7580725\/7590615\/07590979.pdf?arnumber=7590979","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T18:37:54Z","timestamp":1755196674000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/7590979\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":23,"URL":"https:\/\/doi.org\/10.1109\/embc.2016.7590979","relation":{},"subject":[],"published":{"date-parts":[[2016,8]]}}}