{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T23:37:37Z","timestamp":1768347457971,"version":"3.49.0"},"reference-count":24,"publisher":"IEEE","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/501100013209","name":"Hellenic Foundation for Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013209","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,1]]},"DOI":"10.1109\/embc46164.2021.9629912","type":"proceedings-article","created":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T21:24:16Z","timestamp":1639085056000},"page":"1670-1673","source":"Crossref","is-referenced-by-count":6,"title":["Multiple additive regression trees with hybrid loss for classification tasks across heterogeneous clinical data in distributed environments: a case study"],"prefix":"10.1109","author":[{"given":"Vasileios C.","family":"Pezoulas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Themis P.","family":"Exarchos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios G.","family":"Tzioufas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios I.","family":"Fotiadis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"ref10","first-page":"mjaa030","article-title":"Modern deep learning in bioinformatics","author":"li","year":"2020","journal-title":"Journal of Molecular Cell Biology"},{"key":"ref11","first-page":"3","article-title":"Incremental gradient, subgradient, and proximal methods for convex optimization: A survey","volume":"2010","author":"bertsekas","year":"2011","journal-title":"Optimization for Machine Learning"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-64610-3_36"},{"key":"ref13","first-page":"823","article-title":"Utilizing incremental learning for the prediction of disease outcomes across distributed clinical data: A framework and a case study","author":"pezoulas","year":"2019","journal-title":"Proceedings of the Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON)"},{"key":"ref14","first-page":"489","article-title":"Dart: Dropouts meet multiple additive regression trees","author":"vinayak","year":"2015","journal-title":"Proceedings of the Artificial Intelligence and Statistics"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1145\/2939672.2939785"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2019.03.001"},{"key":"ref17","year":"0"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1109\/RBME.2018.2855055"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s40745-020-00253-5"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s40537-019-0217-0"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijinfomgt.2020.102078"},{"key":"ref6","article-title":"Big data analytics and its benefits in healthcare","volume":"66","author":"kumar","year":"2019","journal-title":"Big Data and Health Analytics"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4324\/9780429022241"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-39568-1"},{"key":"ref7","article-title":"A review of big data and its applications in healthcare and public sector","volume":"66","author":"shastri","year":"2019","journal-title":"Big Data and Health Analytics"},{"key":"ref2","author":"pezoulas","year":"2020","journal-title":"Medical Data Sharing Harmonization and Analytics"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-019-0727-5"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1109\/MSP.2020.2972654"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.2018.1543124"},{"key":"ref22","author":"robnik-sikonja","year":"2019","journal-title":"Package ‘semiArtificial’ CRAN"},{"key":"ref21","first-page":"5343","article-title":"Generation of virtual patient data for insilico cardiomyopathies drug development using tree ensembles: a comparative study","author":"pezoulas","year":"2020","journal-title":"Proceedings of the 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.30699\/fhi.v8i1.180"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.594096"}],"event":{"name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","location":"Mexico","start":{"date-parts":[[2021,11,1]]},"end":{"date-parts":[[2021,11,5]]}},"container-title":["2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/9629355\/9629471\/09629912.pdf?arnumber=9629912","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T16:54:13Z","timestamp":1652201653000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/9629912\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,1]]},"references-count":24,"URL":"https:\/\/doi.org\/10.1109\/embc46164.2021.9629912","relation":{},"subject":[],"published":{"date-parts":[[2021,11,1]]}}}