{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T01:21:56Z","timestamp":1740100916787,"version":"3.37.3"},"reference-count":14,"publisher":"IEEE","license":[{"start":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T00:00:00Z","timestamp":1657497600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T00:00:00Z","timestamp":1657497600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/501100001381","name":"National Research Foundation Singapore","doi-asserted-by":"publisher","award":["NRF-CRP22-2019-0003"],"award-info":[{"award-number":["NRF-CRP22-2019-0003"]}],"id":[{"id":"10.13039\/501100001381","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,11]]},"DOI":"10.1109\/embc48229.2022.9871875","type":"proceedings-article","created":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T20:02:05Z","timestamp":1662667325000},"page":"1647-1650","source":"Crossref","is-referenced-by-count":2,"title":["CycleDNN - A Novel Deep Neural Network Model for CETSA Feature Prediction cross Cell Lines"],"prefix":"10.1109","author":[{"given":"Zeng","family":"Zeng","sequence":"first","affiliation":[{"name":"Agency for Science, Technology and Research, Institute for Infocomm Research (I2R),Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shenghao","family":"Zhao","sequence":"additional","affiliation":[{"name":"National University of Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Da","sequence":"additional","affiliation":[{"name":"National University of Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peisheng","family":"Qian","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research, Institute for Infocomm Research (I2R),Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam Wai","family":"Leong","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR), Genome Institute of Singapore (GIS)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingyun","family":"Dai","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Southern University of Science and Technology,Shenzhen,China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Par","family":"Nordlund","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR), Institute of Molecular and Cell Biology,Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nayana","family":"Prabhu","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR), Institute of Molecular and Cell Biology,Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyuan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research, Institute for Infocomm Research (I2R),Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xulei","family":"Yang","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research, Institute for Infocomm Research (I2R),Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1109\/CVPR.2019.00312"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.23919\/BIOSIG.2018.8553377"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1109\/CVPR.2018.00917"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1109\/CVPR.2018.00916"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan0346"},{"key":"ref4","doi-asserted-by":"crossref","DOI":"10.1146\/annurev-pharmtox-010715-103715","article-title":"The cellular thermal shift assay: A novel biophysical assay for in situ drug target engagement and mechanistic biomarker studies","author":"martinez molina","year":"2016","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"ref3","doi-asserted-by":"crossref","DOI":"10.1038\/nprot.2014.138","article-title":"The cellular thermal shift assay for evaluating drug target interactions in cells","author":"jafari","year":"2014","journal-title":"Nature Protocols"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1145\/3065386","article-title":"Imagenet classification with deep convolutional neural networks","volume":"60","author":"krizhevsky","year":"2017","journal-title":"Communications of the ACM"},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.1146\/annurev-biochem-062917-012837","article-title":"Horizontal cell biology: Monitoring global changes of protein interaction states with the proteome-wide cellular thermal shift assay (cetsa)","author":"dai","year":"2019","journal-title":"Annu Rev Biochem"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1109\/ICCV.2017.244"},{"key":"ref7","article-title":"Image-to-image translation with conditional adversarial networks","author":"isola","year":"2017","journal-title":"Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition"},{"key":"ref2","article-title":"Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay","author":"martinez molina","year":"2013","journal-title":"Science"},{"key":"ref1","article-title":"Integrated identification of disease specific pathways using multi-omics data","author":"lu","year":"2019","journal-title":"BioRxiv"},{"key":"ref9","article-title":"Generative adversarial nets","author":"goodfellow","year":"2014","journal-title":"Adv Neural Inf Process Syst"}],"event":{"name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","start":{"date-parts":[[2022,7,11]]},"location":"Glasgow, Scotland, United Kingdom","end":{"date-parts":[[2022,7,15]]}},"container-title":["2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/9870821\/9870822\/09871875.pdf?arnumber=9871875","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T20:59:54Z","timestamp":1664225994000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/9871875\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,11]]},"references-count":14,"URL":"https:\/\/doi.org\/10.1109\/embc48229.2022.9871875","relation":{},"subject":[],"published":{"date-parts":[[2022,7,11]]}}}