{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T05:21:50Z","timestamp":1738473710706,"version":"3.35.0"},"reference-count":30,"publisher":"IEEE","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1109\/ijcnn.2008.4633952","type":"proceedings-article","created":{"date-parts":[[2008,9,29]],"date-time":"2008-09-29T20:31:26Z","timestamp":1222720286000},"page":"1199-1206","source":"Crossref","is-referenced-by-count":0,"title":["A novel strategy for the structure-based drug design of heat shock protein 90 inhibitors"],"prefix":"10.1109","author":[{"family":"Omix Yu-Chian Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Guan-Wen Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Winston Yu-Chen Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"19","doi-asserted-by":"publisher","DOI":"10.1021\/jm060999m"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2007.08.069"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1021\/ci0342728"},{"year":"0","key":"15"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2005.08.092"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2004.10.010"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2004.08.036"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1021\/jm0603116"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-1892"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2005.02.022"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmgm.2007.02.002"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1799"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2007.03.048"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1021\/jm051296s"},{"journal-title":"Binding mode analyses and pharmacophore model development for sulfonamide chalcone derivatives a new class of alpha-glucosidase inhibitors J Mol Graph Model","year":"2007","author":"bharatham","key":"25"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmgm.2007.07.002"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1002\/prot.21844"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmgm.2007.05.005"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-8-27"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.19.1564"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2006.01.006"},{"key":"10","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1158\/1535-7163.1021.3.8","article-title":"altered hsp90 function in cancer: a unique therapeutic opportunity","volume":"3","author":"bagatell","year":"2004","journal-title":"Mol Cancer Ther"},{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/1439-7633(20020902)3:9<807::AID-CBIC807>3.0.CO;2-A"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1021\/jm050355z"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2004.03.033"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/17.16.4829"},{"key":"5","first-page":"2139","article-title":"inhibition of heat shock protein 90 function down-regulates akt kinase and sensitizes tumors to taxol","volume":"63","author":"solit","year":"2003","journal-title":"Cancer Res"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M410838200"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1021\/jm060297x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1021\/ja043101w"}],"event":{"name":"2008 IEEE International Joint Conference on Neural Networks (IEEE World Congress on Computational Intelligence)","start":{"date-parts":[[2008,6,1]]},"location":"Hong Kong","end":{"date-parts":[[2008,6,8]]}},"container-title":["2008 IEEE International Joint Conference on Neural Networks (IEEE World Congress on Computational Intelligence)"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx5\/4625775\/4633757\/04633952.pdf?arnumber=4633952","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T08:28:59Z","timestamp":1738398539000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/4633952\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":30,"URL":"https:\/\/doi.org\/10.1109\/ijcnn.2008.4633952","relation":{},"subject":[],"published":{"date-parts":[[2008,6]]}}}