{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:18:01Z","timestamp":1787012281811,"version":"build-2736575974"},"reference-count":51,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"5","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2019M650069"],"award-info":[{"award-number":["2019M650069"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2020M670939"],"award-info":[{"award-number":["2020M670939"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province","doi-asserted-by":"publisher","award":["LH2019F049 and LH2019A029"],"award-info":[{"award-number":["LH2019F049 and LH2019A029"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Heilongjiang Postdoctoral Scientific Research Staring Foundation","award":["BHLQ18104"],"award-info":[{"award-number":["BHLQ18104"]}]},{"name":"the Foundation of Graduate Innovative Research","award":["YJSCX2020-073HLJU"],"award-info":[{"award-number":["YJSCX2020-073HLJU"]}]},{"name":"Fundamental Research Foundation of Universities in Heilongjiang Province for Youth Innovation Team","award":["RCYJTD201805"],"award-info":[{"award-number":["RCYJTD201805"]}]},{"name":"Innovation Talents Project of Harbin Science and Technology Bureau","award":["2017RAQXJ094"],"award-info":[{"award-number":["2017RAQXJ094"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61972135"],"award-info":[{"award-number":["61972135"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fundamental Research Foundation of Universities in Heilongjiang Province for Technology Innovation","award":["KJCX201805"],"award-info":[{"award-number":["KJCX201805"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE J. Biomed. Health Inform."],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1109\/jbhi.2020.3039502","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T15:21:39Z","timestamp":1605885699000},"page":"1793-1804","source":"Crossref","is-referenced-by-count":59,"title":["Graph Convolutional Autoencoder and Fully-Connected Autoencoder with Attention Mechanism Based Method for Predicting Drug-Disease Associations"],"prefix":"10.1109","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5328-691X","authenticated-orcid":false,"given":"Ping","family":"Xuan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0306-9009","authenticated-orcid":false,"given":"Nan","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiangang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiya","family":"Nakaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq241"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btz182"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-019-2127-5"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.01301"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1186\/1755-8794-6-S3-S4"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-15716-8"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1145\/3097983.3098036"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2426958"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.3390\/cells8070705"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2019.00924"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu403"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw770"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2016.2550453"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-802103-3.00002-X"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2018.06.012"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw228"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbv066"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty013"},{"key":"ref24","first-page":"47","article-title":"MicroRNA-small molecule association identification: From experimental results to computational models","volume":"21","author":"chen","year":"2020","journal-title":"Brief Bioinf"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1080\/15476286.2019.1694732"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/psp.2014.44"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1021\/ci500340n"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky868"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx1037"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2174\/0929867325666180530100332"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2174\/1568026615666150112103510"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv951"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2013.1"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbv020"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004975"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2011.26"},{"key":"ref16","first-page":"1","article-title":"Drug repositioning by kernel-based integration of molecular structure, molecular activity, and phenotype data","volume":"8","author":"wang","year":"2013","journal-title":"PLoS ONE"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-018-2220-4"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1109\/BIBM.2018.8621191"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-016-1336-7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1109\/JBHI.2018.2856535"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2018.168"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4103\/0022-3859.81870"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1109\/JBHI.2020.2991763"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00896"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27604"},{"key":"ref49","article-title":"Management of spasticity with severe painful myoclonic jerks in an operated case of spinal astrocytoma","volume":"58","author":"jain","year":"2014","journal-title":"Indian J Anaesth"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1358\/dnp.2009.22.2.1343228"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1142\/9789813207813_0014"},{"key":"ref45","article-title":"Adam: A method for stochastic optimization","author":"kingma","year":"2014"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118432"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-44886-1_25"},{"key":"ref42","article-title":"UniProt: The universal protein knowledgebase","volume":"46","author":"consortium","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1243"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1089\/cmb.2010.0213"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbt056"}],"container-title":["IEEE Journal of Biomedical and Health Informatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/6221020\/9428033\/09265200.pdf?arnumber=9265200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T10:53:24Z","timestamp":1652180004000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/9265200\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":51,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.1109\/jbhi.2020.3039502","relation":{},"ISSN":["2168-2194","2168-2208"],"issn-type":[{"value":"2168-2194","type":"print"},{"value":"2168-2208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}