{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T05:12:42Z","timestamp":1784956362603,"version":"3.55.0"},"reference-count":31,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/100007927","name":"University of Oklahoma Health Sciences Center","doi-asserted-by":"publisher","award":["3P30CA225520"],"award-info":[{"award-number":["3P30CA225520"]}],"id":[{"id":"10.13039\/100007927","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Faculty Investment Program from the University of Oklahoma"},{"name":"Institutional Research from the American Cancer Society","award":["IRG-19-142-01"],"award-info":[{"award-number":["IRG-19-142-01"]}]},{"name":"Oklahoma Shared Clinical and Translational Resources","award":["NIGMS U54GM104938"],"award-info":[{"award-number":["NIGMS U54GM104938"]}]},{"DOI":"10.13039\/501100008982","name":"National Science Foundation","doi-asserted-by":"publisher","award":["OIA-2132161"],"award-info":[{"award-number":["OIA-2132161"]}],"id":[{"id":"10.13039\/501100008982","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute of Health","award":["R01DK133717"],"award-info":[{"award-number":["R01DK133717"]}]},{"name":"Medical Imaging COBRE","award":["P20 GM135009"],"award-info":[{"award-number":["P20 GM135009"]}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P20GM103639"],"award-info":[{"award-number":["P20GM103639"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30CA225520"],"award-info":[{"award-number":["P30CA225520"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Biomed. Eng."],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1109\/tbme.2022.3231835","type":"journal-article","created":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T18:37:01Z","timestamp":1671820621000},"page":"1891-1901","source":"Crossref","is-referenced-by-count":8,"title":["Optical Coherence Tomography of Tumor Spheroids Identifies Candidates for Drug Repurposing in Ovarian Cancer"],"prefix":"10.1109","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9926-7554","authenticated-orcid":false,"given":"Feng","family":"Yan","sequence":"first","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Hee","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, The University of Oklahoma Health Sciences Center, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyang","family":"Yan","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam B.","family":"Ton","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Wang","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6775-9228","authenticated-orcid":false,"given":"Bornface","family":"Mutembei","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2467-5590","authenticated-orcid":false,"given":"Zaid A.","family":"Alhajeri","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aubrey F.","family":"McNiel","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Keddissi","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muralidharan","family":"Jayaraman","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, The University of Oklahoma Health Sciences Center, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny N.","family":"Dhanasekaran","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9499-5384","authenticated-orcid":false,"given":"Qinggong","family":"Tang","sequence":"additional","affiliation":[{"name":"Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s10529-006-9232-2"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.428197"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2008.061244"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-15-0419"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21207703"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2004088"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.440444"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.404336"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiotec.2010.01.012"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21208"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1695"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-04-495366"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.2174\/1381612003401046"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2016.11.002"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2018.11.023"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-1624"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/cas.13434"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3390\/biom8010007"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e10-04-0335"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2013.00051"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2013.00062"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-1789"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3390\/cancers10100358"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-12-0095"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.425512"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-0821"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1126\/science.1957169"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2006.03.011"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2012.708334"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/bit.26845"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0130348"}],"container-title":["IEEE Transactions on Biomedical Engineering"],"original-title":[],"link":[{"URL":"https:\/\/ieeexplore.ieee.org\/ielam\/10\/10129246\/9998062-aam.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/10\/10129246\/09998062.pdf?arnumber=9998062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T18:30:51Z","timestamp":1687804251000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/9998062\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":31,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.1109\/tbme.2022.3231835","relation":{},"ISSN":["0018-9294","1558-2531"],"issn-type":[{"value":"0018-9294","type":"print"},{"value":"1558-2531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]}}}