{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T08:16:24Z","timestamp":1778055384996,"version":"3.51.4"},"reference-count":66,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"3","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61373062"],"award-info":[{"award-number":["61373062"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61175024"],"award-info":[{"award-number":["61175024"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61222306"],"award-info":[{"award-number":["61222306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61100116"],"award-info":[{"award-number":["61100116"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61233011"],"award-info":[{"award-number":["61233011"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu","doi-asserted-by":"publisher","award":["BK20141403"],"award-info":[{"award-number":["BK20141403"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Jiangsu Postdoctoral Science Foundation","award":["1201027C"],"award-info":[{"award-number":["1201027C"]}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2013M530260"],"award-info":[{"award-number":["2013M530260"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2014T70526"],"award-info":[{"award-number":["2014T70526"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002949","name":"Jiangsu Province","doi-asserted-by":"publisher","award":["2013-XXRJ-022"],"award-info":[{"award-number":["2013-XXRJ-022"]}],"id":[{"id":"10.13039\/501100002949","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"crossref","award":["30920130111010"],"award-info":[{"award-number":["30920130111010"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE\/ACM Trans. Comput. Biol. and Bioinf."],"published-print":{"date-parts":[[2015,5,1]]},"DOI":"10.1109\/tcbb.2014.2359451","type":"journal-article","created":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T15:53:07Z","timestamp":1417017187000},"page":"611-621","source":"Crossref","is-referenced-by-count":19,"title":["Disulfide Connectivity Prediction Based on Modelled Protein 3D Structural Information and Random Forest Regression"],"prefix":"10.1109","volume":"12","author":[{"given":"Dong-Jun","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi-Bei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-Yu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Bin","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/17.10.957"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl189"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti715"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl266"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2443.2010.01434.x"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1126\/science.1091724"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010933404324"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.2174\/138920307780831848"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm637"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm505"},{"key":"ref60","author":"richard","year":"2001","journal-title":"Pattern Classification"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1016\/j.patcog.2013.09.038"},{"key":"ref61","first-page":"507","article-title":"Laplacian score for feature selection","author":"he","year":"2005","journal-title":"Proc Adv Neural Inf Process Syst"},{"key":"ref63","article-title":"Prediction of protein-protein interaction sites in sequences and 3D structures by random forests","volume":"5","author":"\u0161iki?","year":"2009","journal-title":"PLoS Comput Biol"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21968"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp648"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt344"},{"key":"ref65","first-page":"30","article-title":"Publication decisions and their possible effects on inferences drawn from tests of significance–or vice versa","volume":"54","author":"sterlinga","year":"1959","journal-title":"J Amer Statist Assoc"},{"key":"ref66","article-title":"The PyMOL molecular graphics system","year":"0"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.10.034"},{"key":"ref2","article-title":"Studies on the principles that govern the folding of protein chains","author":"anfinsen","year":"1972"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nsb0295-171"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2010.08.029"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm505"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002\/prot.21309"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq514"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21433"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"10s","DOI":"10.1186\/1471-2105-14-S1-S10","article-title":"Prediction of disulfide connectivity in proteins with machine-learning methods and correlated mutations","volume":"14","author":"savojardo","year":"2013","journal-title":"BMC Bioinformatics"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr387"},{"key":"ref50","first-page":"233","article-title":"On assessing prior distributions and Bayesian regression analysis with g-prior distributions","volume":"6","author":"zellner","year":"1986","journal-title":"Bayesian Inference and Decision Techniques Fssays in Honor of Bruno de Finetti"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1142\/S0219720005001077"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl230"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti033"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-5-64"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bth282"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm344"},{"key":"ref54","first-page":"18","article-title":"Classification and regression by random forest","volume":"2","author":"liaw","year":"2002","journal-title":"R News"},{"key":"ref53","first-page":"1889","article-title":"Working set selection using second order information for training SVM","volume":"6","author":"fan","year":"2005","journal-title":"J Mach Learn Res"},{"key":"ref52","author":"vapnik","year":"1998","journal-title":"Statistical Learning Theory"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks1226"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr387"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2013.05.022"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-159"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1109\/TNB.2011.2160730","article-title":"SOMRuler: A novel interpretable transmembrane helices predictor","volume":"10","author":"yu","year":"2011","journal-title":"IEEE Trans Nanobiosci"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2008.140"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/285378a0"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1142\/S0219720011005355"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2011.05.004"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2008.27"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts598"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0958-1669(98)80012-8"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0300-9084(90)90115-W"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/0471250953.bi0506s15"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2010.5"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq373"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.3091"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-9-40"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2010.06.169"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucom.2012.10.012"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2013.104"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-7-425"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-7-124"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl158"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-60761-977-2_2"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/29.14.2994"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056621"}],"container-title":["IEEE\/ACM Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/8857\/7116662\/06967829.pdf?arnumber=6967829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T11:30:09Z","timestamp":1641987009000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/6967829\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,1]]},"references-count":66,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1109\/tcbb.2014.2359451","relation":{},"ISSN":["1545-5963","1557-9964","2374-0043"],"issn-type":[{"value":"1545-5963","type":"print"},{"value":"1557-9964","type":"electronic"},{"value":"2374-0043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,1]]}}}