{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T06:47:25Z","timestamp":1784357245910,"version":"3.55.0"},"reference-count":40,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/legalcode"}],"funder":[{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/M017982\/1"],"award-info":[{"award-number":["BB\/M017982\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"name":"School of Engineering of the University of Warwick"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE\/ACM Trans. Comput. Biol. and Bioinf."],"published-print":{"date-parts":[[2019,3,1]]},"DOI":"10.1109\/tcbb.2017.2771775","type":"journal-article","created":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T19:41:44Z","timestamp":1515699704000},"page":"583-595","source":"Crossref","is-referenced-by-count":19,"title":["Modelling and Control of Gene Regulatory Networks for Perturbation Mitigation"],"prefix":"10.1109","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1400-2659","authenticated-orcid":false,"given":"Mathias","family":"Foo","sequence":"first","affiliation":[{"name":"School of Engineering, Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3456-6614","authenticated-orcid":false,"given":"Jongrae","family":"Kim","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering, University of Leeds, Leeds, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1395-9846","authenticated-orcid":false,"given":"Declan G.","family":"Bates","sequence":"additional","affiliation":[{"name":"School of Engineering, Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1109\/TBCAS.2015.2458435"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2010.07.034"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.cam.2015.10.004"},{"key":"ref32","first-page":"107","article-title":"Weighting of linear plots in enzyme kinetics","volume":"2","author":"cornish-bowden","year":"1982","journal-title":"Journal of Molecular Science"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.2307\/2529871"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1042\/bj1490775"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/j.mbs.2013.11.002"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiotec.2010.02.019"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1016\/0270-0255(86)90076-X"},{"key":"ref34","first-page":"101","article-title":"Estimation aspects of the Michaelis-Menten model","volume":"14","author":"toulias","year":"2017","journal-title":"RevStat Statist J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1603992113"},{"key":"ref40","author":"soderstrom","year":"1988","journal-title":"System Identification"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1109\/ICNSC.2017.8000094"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1089\/cmb.2008.09TT"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1407.021"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.04497.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ifacol.2017.08.2237"},{"key":"ref16","author":"ogata","year":"2010","journal-title":"Modern Control Engineering"},{"key":"ref17","author":"savageau","year":"1976","journal-title":"Biochemical Systems Analysis A Study of Function and Design in Molecular Biology"},{"key":"ref18","author":"voit","year":"1991","journal-title":"Canonical Nonlinear Modeling S-system Approach to Understanding Complexity"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btg027"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003705"},{"key":"ref4","first-page":"130","article-title":"Journal of hydroinformatics","volume":"17","author":"schwanenberg","year":"2015","journal-title":"Open Real-Time Control (RTC)-Tools Softw Framework Model RTC Water Resources Sytems"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2016.00590"},{"key":"ref3","first-page":"9","article-title":"Realistic control of network dynamics","volume":"4","author":"cornelius","year":"2012","journal-title":"Nature Commun"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/nature10011"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1080\/08948550302453","article-title":"A century of enzyme kinetics: Reliability of the $K_{M}$KM and $v_{max}$vmax estimates","volume":"8","author":"schnell","year":"2003","journal-title":"Comments Theoretical Biol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/rnc.3504"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1103\/RevModPhys.88.035006"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2015.2485226"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1109\/TIA.2011.2168932"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1109\/MCS.2015.2495000"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1109\/JPROC.2006.887289"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti071"},{"key":"ref22","author":"ljung","year":"1999","journal-title":"System Identification Theory for the User"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1021\/bi00395a042"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1075"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1126\/science.1081900"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/0025-5564(82)90061-X"},{"key":"ref25","article-title":"How to infer gene networks from expression profiles","volume":"78","author":"bansal","year":"2007","journal-title":"Molecular Syst Biol"}],"container-title":["IEEE\/ACM Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/8857\/8680721\/08254368.pdf?arnumber=8254368","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T17:41:05Z","timestamp":1715708465000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/8254368\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,1]]},"references-count":40,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1109\/tcbb.2017.2771775","relation":{},"ISSN":["1545-5963","1557-9964","2374-0043"],"issn-type":[{"value":"1545-5963","type":"print"},{"value":"1557-9964","type":"electronic"},{"value":"2374-0043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,1]]}}}