{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T07:57:16Z","timestamp":1778227036106,"version":"3.51.4"},"reference-count":44,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"5","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"name":"Department of Computer Science, College of Computing and Informatics"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE\/ACM Trans. Comput. Biol. and Bioinf."],"published-print":{"date-parts":[[2020,9,1]]},"DOI":"10.1109\/tcbb.2019.2907246","type":"journal-article","created":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T18:21:20Z","timestamp":1553538080000},"page":"1613-1624","source":"Crossref","is-referenced-by-count":6,"title":["Causal Disturbance Analysis: A Novel Graph Centrality Based Method for Pathway Enrichment Analysis"],"prefix":"10.1109","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4693-8331","authenticated-orcid":false,"given":"Pourya Naderi","family":"Yeganeh","sequence":"first","affiliation":[{"name":"Department of Computer Science, College of Computing and Informatics, University of North Carolina at Charlotte, Charlotte, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Taghi","family":"Mostafavi","sequence":"additional","affiliation":[{"name":"Department of Computer Science, College of Computing and Informatics, University of North Carolina at Charlotte, Charlotte, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2010.09.011"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1038\/nm1087"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.3641"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(03)00248-4"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2644"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1038\/nrc969"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/93.14.1062"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63370-6"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2015.02.003"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.2011.639361"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1145\/3107411.3107488"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.553"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts389"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btn577"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/35052073"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1998.106"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780199206650.001.0001"},{"key":"ref16","author":"schloerke","year":"2018","journal-title":"GGally Extension to ’ggplot2’"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1137\/1.9780898719512"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8733(01)00038-7"},{"key":"ref19","first-page":"559","article-title":"Combining independent tests of significance","volume":"49","author":"birnbaum","year":"1954","journal-title":"J Amer Statistical Assoc"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2004-5-10-r80"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1092"},{"key":"ref27","article-title":"An algorithm for fast preranked gene set enrichment analysis using cumulative statistic calculation","author":"sergushichev","year":"2016","journal-title":"BioRxiv"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/75556"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.18632\/genesandcancer.164"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002375"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2102"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/35075138"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000543"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/1752-0509-6-56"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506580102"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-08-0193"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv007"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-2884"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-17-0749"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp167"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-2463"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"ref44","first-page":"414","article-title":"Combining multiple tools outperforms individual methods in gene set enrichment analyses","volume":"33","author":"alhamdoosh","year":"2017","journal-title":"Bioinf"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-161"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2013.515"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw410"}],"container-title":["IEEE\/ACM Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/8857\/9216708\/08673887.pdf?arnumber=8673887","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T20:24:58Z","timestamp":1722457498000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/8673887\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,1]]},"references-count":44,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.1109\/tcbb.2019.2907246","relation":{},"ISSN":["1545-5963","1557-9964","2374-0043"],"issn-type":[{"value":"1545-5963","type":"print"},{"value":"1557-9964","type":"electronic"},{"value":"2374-0043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,1]]}}}