{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:27:22Z","timestamp":1771921642140,"version":"3.50.1"},"reference-count":64,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"2","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE\/ACM Trans. Comput. Biol. and Bioinf."],"published-print":{"date-parts":[[2021,3,1]]},"DOI":"10.1109\/tcbb.2019.2927310","type":"journal-article","created":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T20:09:16Z","timestamp":1562702956000},"page":"708-717","source":"Crossref","is-referenced-by-count":27,"title":["Relation Prediction of Co-Morbid Diseases Using Knowledge Graph Completion"],"prefix":"10.1109","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1852-0146","authenticated-orcid":false,"given":"Saikat","family":"Biswas","sequence":"first","affiliation":[]},{"given":"Pabitra","family":"Mitra","sequence":"additional","affiliation":[]},{"given":"Krothapalli Sreenivasa","family":"Rao","sequence":"additional","affiliation":[]}],"member":"263","reference":[{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1005968"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1093\/database\/bat080"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1071d","DOI":"10.1093\/nar\/gku1011","article-title":"Disease ontology 2015 update: An expanded and updated database of human diseases for linking biomedical knowledge through disease data","volume":"43","author":"kibbe","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"966d","DOI":"10.1093\/nar\/gkt1026","article-title":"The human phenotype ontology project: Linking molecular biology and disease through phenotype data","volume":"42","author":"k\u00f6hler","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1038\/75556"},{"key":"ref30","article-title":"Deep learning on biological knowledge graphs","author":"maddouri","year":"2017"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1038\/ng0504-431"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199809000-00060"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2009.98"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"561d","DOI":"10.1093\/nar\/gkq973","article-title":"The string database in 2011: Functional interaction networks of proteins, globally integrated and scored","volume":"39","author":"szklarczyk","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00405"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2012.01775.x"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2011.0057"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1145\/2623330.2623732"},{"key":"ref28","article-title":"OBO flat file format syntax and semantics and mapping to owl web ontology language","author":"horrocks","year":"2007"},{"key":"ref64","first-page":"3111","article-title":"Distributed representations of words and phrases and their compositionality","author":"mikolov","year":"2013","journal-title":"Proc Int Conf Neural Inf Process"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.websem.2008.05.001","article-title":"OWL 2: The next step for OWL","volume":"6","author":"grau","year":"2008","journal-title":"Web Semantics Sci Serv Agents World Wide Web"},{"key":"ref29","doi-asserted-by":"crossref","DOI":"10.1038\/nature14539","article-title":"Deep learning","volume":"521","author":"lecun","year":"2015","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1145\/1376616.1376746"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1145\/2623330.2623623"},{"key":"ref20","author":"wood","year":"2014","journal-title":"Linked data"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.03.004"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"204d","DOI":"10.1093\/nar\/gku989","article-title":"UniProt: A hub for protein information","volume":"43","author":"consortium","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1202d","DOI":"10.1093\/nar\/gkv951","article-title":"Pubchem substance and compound databases","volume":"44","author":"kim","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt765"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/srep10888"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1006\/ijhc.1995.1081"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2011.29"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1038\/srep00757"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2014.12.012"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfu231"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.5500\/wjt.v3.i4.91"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1681\/ASN.V113454","article-title":"Relationship between expression of bcl-2 genes and growth factors in ischemic acute renal failure in the rat","volume":"11","author":"gobe","year":"2000","journal-title":"J Amer Soc Nephrology"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.07.020"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-015-0526-8"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1186\/ar3256"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.5230\/jgc.2013.13.2.106"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1145\/1835804.1835916"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1145\/2187836.2187874"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btx441"},{"key":"ref12","first-page":"2787","article-title":"Translating embeddings for modeling multi- relational data","author":"bordes","year":"2013","journal-title":"Proc Int Conf Neural Inf Process"},{"key":"ref13","first-page":"2071","article-title":"Complex embeddings for simple link prediction","author":"trouillon","year":"2016","journal-title":"Int Conf Mach Learn"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.18653\/v1\/D15-1082"},{"key":"ref15","first-page":"926","article-title":"Reasoning with neural tensor networks for knowledge base completion","author":"socher","year":"2013","journal-title":"Proc Int Conf Neural Inf Process"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/sapm192761164"},{"key":"ref17","article-title":"Embedding entities and relations for learning and inference in knowledge bases","author":"yang","year":"0","journal-title":"Int Conf on Learning Representations"},{"key":"ref18","first-page":"4735","article-title":"Knowledge graph completion via complex tensor factorization","volume":"18","author":"trouillon","year":"2017","journal-title":"J Mach Learn Res"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2005-6-5-r46"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3233\/SW-140134"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.7551\/mitpress\/7287.003.0008"},{"key":"ref6","article-title":"Toward an architecture for never-ending language learning","volume":"5","author":"carlson","year":"2010","journal-title":"Proc 24th AAAI Conf Artif Intell"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1145\/1242572.1242667"},{"key":"ref8","first-page":"2468","article-title":"ProbLog: A probabilistic prolog and its application in link discovery","author":"de raedt","year":"2007","journal-title":"Proc 20th Int Joint Conf Artif Intell"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/2041-1480-5-5"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-12-99"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-78652-8_4"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.18653\/v1\/D18-2024"},{"key":"ref45","article-title":"Graph clustering by flow simulation","author":"van dongen","year":"2000"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1186\/2043-9113-4-8"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2016.2550443"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2009.16"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0701361104"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1038\/srep39433"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btx275"}],"container-title":["IEEE\/ACM Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/8857\/9391749\/08758152.pdf?arnumber=8758152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T10:43:24Z","timestamp":1643193804000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/8758152\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,1]]},"references-count":64,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1109\/tcbb.2019.2927310","relation":{},"ISSN":["1545-5963","1557-9964","2374-0043"],"issn-type":[{"value":"1545-5963","type":"print"},{"value":"1557-9964","type":"electronic"},{"value":"2374-0043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,1]]}}}