{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T06:19:24Z","timestamp":1775801964425,"version":"3.50.1"},"reference-count":54,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"6","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61832019"],"award-info":[{"award-number":["61832019"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61772552"],"award-info":[{"award-number":["61772552"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","award":["B18059"],"award-info":[{"award-number":["B18059"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002767","name":"Hunan Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2018WK4001"],"award-info":[{"award-number":["2018WK4001"]}],"id":[{"id":"10.13039\/501100002767","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010083","name":"Hunan Provincial Innovation Foundation For Postgraduate","doi-asserted-by":"publisher","award":["CX20190123"],"award-info":[{"award-number":["CX20190123"]}],"id":[{"id":"10.13039\/501100010083","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE\/ACM Trans. Comput. Biol. and Bioinf."],"published-print":{"date-parts":[[2021,11,1]]},"DOI":"10.1109\/tcbb.2020.2973148","type":"journal-article","created":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T21:19:07Z","timestamp":1581455947000},"page":"2483-2491","source":"Crossref","is-referenced-by-count":54,"title":["FUNMarker: Fusion Network-Based Method to Identify Prognostic and Heterogeneous Breast Cancer Biomarkers"],"prefix":"10.1109","volume":"18","author":[{"given":"Xingyi","family":"Li","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3045-5706","authenticated-orcid":false,"given":"Ju","family":"Xiang","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1516-0480","authenticated-orcid":false,"given":"Jianxin","family":"Wang","sequence":"additional","affiliation":[]},{"given":"Jinyan","family":"Li","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4593-9332","authenticated-orcid":false,"given":"Fang-Xiang","family":"Wu","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0188-1394","authenticated-orcid":false,"given":"Min","family":"Li","sequence":"additional","affiliation":[]}],"member":"263","reference":[{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.10.050"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"833d","DOI":"10.1093\/nar\/gkw943","article-title":"DisGeNET: A comprehensive platform integrating information on human disease-associated genes and variants","volume":"45","author":"pi\u00f1ero","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506230102"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17947-1"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1186\/bcr1325"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/30.1.207"},{"key":"ref37","first-page":"331d","article-title":"Expansion of the gene ontology knowledgebase and resources","volume":"45","author":"consortium","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1038\/75556"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021967"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-4414"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1186\/gm186"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1126\/science.1253462"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2017.00084"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1126\/science.3798106"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1670"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-11-S9-S5"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/s13048-016-0285-0"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1126\/science.1257601"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt373"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btx487"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/nature12625"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1172\/JCI60534"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp914"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr1122"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-26969-2_50"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000641"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2001699"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-009-0674-9"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbz017"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1038\/nature04209"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2918"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2017.2705143"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.26599\/TST.2018.9010097"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2019.01401"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2673"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002511"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073074"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/med.21293"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1172\/JCI57088"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(00)00254-0"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1038\/415530a","article-title":"Gene expression profiling predicts clinical outcome of breast cancer","volume":"415","author":"van't veer","year":"2002","journal-title":"Nature"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1172\/JCI45014"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-1658"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/nature06913"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0802208105"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1677\/ERC-10-0136"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"698d","DOI":"10.1093\/nar\/gkq1116","article-title":"The BioGRID interaction database: 2011 update","volume":"39","author":"stark","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr930"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkg108"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"767d","DOI":"10.1093\/nar\/gkn892","article-title":"Human protein reference database—2009 update","volume":"37","author":"keshava prasad","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1280"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2005.08.029"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr1088"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1597"}],"container-title":["IEEE\/ACM Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/8857\/9642421\/08994076.pdf?arnumber=8994076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T21:26:12Z","timestamp":1646774772000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/8994076\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,1]]},"references-count":54,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.1109\/tcbb.2020.2973148","relation":{},"ISSN":["1545-5963","1557-9964","2374-0043"],"issn-type":[{"value":"1545-5963","type":"print"},{"value":"1557-9964","type":"electronic"},{"value":"2374-0043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,1]]}}}