{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T15:56:56Z","timestamp":1780588616548,"version":"3.54.1"},"reference-count":55,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE\/ACM Trans. Comput. Biol. and Bioinf."],"published-print":{"date-parts":[[2023,3,1]]},"DOI":"10.1109\/tcbb.2022.3191392","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T19:34:38Z","timestamp":1657913678000},"page":"1009-1019","source":"Crossref","is-referenced-by-count":8,"title":["Explainable Drug Repurposing Approach From Biased Random Walks"],"prefix":"10.1109","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1442-3552","authenticated-orcid":false,"given":"Filippo","family":"Castiglione","sequence":"first","affiliation":[{"name":"Institute for Applied Computing of the National Research Council (CNR&#x2013;IAC) of Italy, Rome, RM, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7601-321X","authenticated-orcid":false,"given":"Christine","family":"Nardini","sequence":"additional","affiliation":[{"name":"Institute for Applied Computing of the National Research Council (CNR&#x2013;IAC) of Italy, Rome, RM, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8391-2563","authenticated-orcid":false,"given":"Elia","family":"Onofri","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Physics, Roma Tre University, Roma, RM, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9016-074X","authenticated-orcid":false,"given":"Marco","family":"Pedicini","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Physics, Roma Tre University, Roma, RM, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3635-7664","authenticated-orcid":false,"given":"Paolo","family":"Tieri","sequence":"additional","affiliation":[{"name":"Institute for Applied Computing of the National Research Council (CNR&#x2013;IAC) of Italy, Rome, RM, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref1","article-title":"Repurposing drugs to treat COVID-19: Interview with David Fajgenbaum","year":"2021"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00270-8"},{"key":"ref3","article-title":"Corona project","year":"2021"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-54849-w"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004975"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.synbio.2018.10.002"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/nature08506"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbv066"},{"issue":"17","key":"ref9","first-page":"2664","article-title":"Drug repositioning based on comprehensive similarity measures and bi-random walk algorithm","volume-title":"Bioinformatics","volume":"32","author":"Luo","year":"2016"},{"issue":"3","key":"ref10","article-title":"Medical subject headings (mesh)","volume":"88","author":"Lipscomb","year":"2000","journal-title":"Bull. Med. Library Assoc."},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx1037"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/cpbi.27"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-019-2858-6"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-018-2142-1"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbaa003"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1039\/c3mb70242a"},{"key":"ref17","article-title":"ICD-11 reference guide: International classification of diseases for mortality and morbidity statistics","author":"Organization"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz1021"},{"key":"ref19","first-page":"1","article-title":"Towards a definition of knowledge graphs","volume-title":"Proc. SEMANTICS 2016: Posters Demos Track","volume":"1695","author":"Ehrlinger"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1145\/567806.567807"},{"key":"ref21","article-title":"CAS registry [online]"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh061"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1012"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1039\/C7RA09229F"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1109\/ACCESS.2020.2976199"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/sdata.2017.29"},{"issue":"7","key":"ref27","article-title":"iDrug: Integration of drug repositioning and drug-target prediction via cross-network embedding","volume-title":"PLoS Comput. Biol.","volume":"16","author":"Chen","year":"2020"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1109\/BIBM.2012.6392722"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-40994-3_37"},{"key":"ref30","article-title":"Drugcentral [internet]"},{"key":"ref31","article-title":"Bethesda (MD): National library of medicine (US)"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa891"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2011.26"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1090\/mbk\/107"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1007\/s13167-019-00195-w"},{"key":"ref36","article-title":"An estimation of the economic impact of chronic noncommunicable diseases in selected countries","volume":"2006","author":"Abegunde","year":"2006"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.17.205732"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10153289"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3916"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1038\/nature12873"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24596"},{"key":"ref42","article-title":"Bethesda (MD): National library of medicine (US)"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1606-80"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1186\/ar3312"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1038\/emm.2016.143"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2018.168"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.2217\/pme-2020-0115"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1109\/TNNLS.2020.3027314"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1126\/science.1105891"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1079"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv1075"},{"key":"ref52","article-title":"DRKG - Drug repurposing knowledge graph for COVID-19","author":"Ioannidis","year":"2020"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz1007"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bby098"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbab328"}],"container-title":["IEEE\/ACM Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/8857\/10091711\/09831014.pdf?arnumber=9831014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T04:22:13Z","timestamp":1716006133000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/9831014\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":55,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1109\/tcbb.2022.3191392","relation":{},"ISSN":["1545-5963","1557-9964","2374-0043"],"issn-type":[{"value":"1545-5963","type":"print"},{"value":"1557-9964","type":"electronic"},{"value":"2374-0043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,1]]}}}