{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T20:27:36Z","timestamp":1773433656856,"version":"3.50.1"},"reference-count":49,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"3","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62072206"],"award-info":[{"award-number":["62072206"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61772381"],"award-info":[{"award-number":["61772381"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Huazhong Agricultural University Scientific & Technological Self-innovation Foundation"},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2662024SZ006"],"award-info":[{"award-number":["2662024SZ006"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Comput. Biol. Bioinform."],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1109\/tcbbio.2025.3548692","type":"journal-article","created":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T18:34:16Z","timestamp":1741286056000},"page":"1052-1059","source":"Crossref","is-referenced-by-count":2,"title":["GNNDRP: Graph Neural Network With Multi-Task Learning for Drug Response Prediction"],"prefix":"10.1109","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6831-600X","authenticated-orcid":false,"given":"Congzhi","family":"Song","sequence":"first","affiliation":[{"name":"College of Informatics, Huazhong Agricultural University, Wuhan, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8684-9950","authenticated-orcid":false,"given":"Xuan","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Informatics, Huazhong Agricultural University, Wuhan, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8040-8836","authenticated-orcid":false,"given":"Zhankun","family":"Xiong","sequence":"additional","affiliation":[{"name":"College of Informatics, Huazhong Agricultural University, Wuhan, China"}]},{"given":"Luotao","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Informatics, Huazhong Agricultural University, Wuhan, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5221-2628","authenticated-orcid":false,"given":"Wen","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Informatics, Huazhong Agricultural University, Wuhan, China"}]}],"member":"263","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/513S8a"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2877"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/nature11003"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.06.017"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004498"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/srep40321"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2018.06.041"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-21622-4"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty848"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2013-14-10-r110"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-11665-4"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2014-15-3-r47"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-015-1492-6"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/srep32679"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3500-5"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2019.05.017"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2018.2819660"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btz825"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2019.2909905"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2019.2910513"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-27214-6"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2019.2919581"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btac383"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btaa822"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2021.3060430"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btab650"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btz621"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbaa243"},{"key":"ref29","article-title":"Self-supervised learning on graphs: Deep insights and new direction","author":"Jin","year":"2020"},{"key":"ref30","first-page":"10871","article-title":"When does self-supervision help graph convolutional networks","volume-title":"Proc. Int. Conf. Mach. Learn.","author":"You"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1186\/1758-2946-4-22"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv951"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-020-00456-1"},{"key":"ref34","article-title":"How powerful are graph neural networks?","author":"Xu","year":"2018"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-019-2910-6"},{"key":"ref36","article-title":"Graph attention networks","author":"Velikovi","year":"2017"},{"key":"ref37","article-title":"Adam: A method for stochastic optimization","author":"Kingma","year":"2014"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1145\/2623330.2623732"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1145\/2939672.2939754"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118432"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-05-718171"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-09-0041"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2012.08.027"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-006-9463-x"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-10-809210"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-016-2254-9"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-02-137737"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S139664"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0133219"}],"container-title":["IEEE Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx8\/10723156\/11025532\/10915569.pdf?arnumber=10915569","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T04:18:36Z","timestamp":1749183516000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/10915569\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":49,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1109\/tcbbio.2025.3548692","relation":{},"ISSN":["2998-4165"],"issn-type":[{"value":"2998-4165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]}}}