{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T12:31:05Z","timestamp":1766061065644,"version":"3.48.0"},"reference-count":50,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"6","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62462030"],"award-info":[{"award-number":["62462030"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62062032"],"award-info":[{"award-number":["62062032"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62472165"],"award-info":[{"award-number":["62472165"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Jiangxi Provincial Natural Science Fund","award":["20252BAC250016"],"award-info":[{"award-number":["20252BAC250016"]}]},{"name":"Jiangxi Provincial Natural Science Fund","award":["20232BAB202025"],"award-info":[{"award-number":["20232BAB202025"]}]},{"name":"Jiangxi Provincial Natural Science Fund","award":["20232BAB202022"],"award-info":[{"award-number":["20232BAB202022"]}]},{"name":"Jiangxi Provincial Natural Science Fund","award":["20204BCJL23035"],"award-info":[{"award-number":["20204BCJL23035"]}]},{"name":"YueLuShan Center Industrial Innovation","award":["2025YCII0126"],"award-info":[{"award-number":["2025YCII0126"]}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of Hunan Province","doi-asserted-by":"publisher","award":["2023JJ30161"],"award-info":[{"award-number":["2023JJ30161"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Comput. Biol. Bioinform."],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1109\/tcbbio.2025.3600428","type":"journal-article","created":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T18:14:49Z","timestamp":1755627289000},"page":"2750-2763","source":"Crossref","is-referenced-by-count":0,"title":["A Cell-Cell Interaction Network Based Method for Identifying Lymph Node Metastasis and Characterizing Lung Cancer Progression"],"prefix":"10.1109","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8645-6815","authenticated-orcid":false,"given":"Xiong","family":"Li","sequence":"first","affiliation":[{"name":"School of Information and Software Engineering, East China Jiaotong University, Nanchang, China"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8637-7472","authenticated-orcid":false,"given":"Chuang","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Information and Software Engineering, East China Jiaotong University, Nanchang, China"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5066-8143","authenticated-orcid":false,"given":"Yixin","family":"Li","sequence":"additional","affiliation":[{"name":"School of Information and Software Engineering, East China Jiaotong University, Nanchang, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4558-652X","authenticated-orcid":false,"given":"Yangkai","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Information and Software Engineering, East China Jiaotong University, Nanchang, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6671-2161","authenticated-orcid":false,"given":"Juan","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Information and Software Engineering, East China Jiaotong University, Nanchang, China"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7464-7467","authenticated-orcid":false,"given":"Xiao","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Information and Software Engineering, East China Jiaotong University, Nanchang, China"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1927-1416","authenticated-orcid":false,"given":"Xuan","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Information and Software Engineering, East China Jiaotong University, Nanchang, China"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4806-453X","authenticated-orcid":false,"given":"Yuchao","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Information and Software Engineering, East China Jiaotong University, Nanchang, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4777-7525","authenticated-orcid":false,"given":"Haowen","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Computer Science and Electronic Engineering, Hunan University, Changsha, China"}]}],"member":"263","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-21-1948"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivab255"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2021.04.048"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-3277"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2021.04.048"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.605977"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s12920-022-01231-x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.10.047"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0698-6"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2022.10.008"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.822315"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-22801-0"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2022.3203185"},{"key":"ref14","first-page":"313","article-title":"Multiclass spectral clustering","volume-title":"Proc. IEEE Int. Conf. Comput. Vis.","author":"Stella","year":"2003"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00824-9"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21246-9"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-022-01064-x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-022-00896-9"},{"key":"ref19","first-page":"265","article-title":"TensorFlow: A system for large-scale machine learning","volume-title":"Proc. 12th USENIX Symp. Operat. Syst. Des. Implementation","author":"Abadi","year":"2016"},{"article-title":"graph2vec: Learning distributed representations of graphs","year":"2017","author":"Narayanan","key":"ref20"},{"key":"ref21","first-page":"2539","article-title":"Weisfeiler-Lehman graph kernels","volume":"12","author":"Shervashidze","year":"2011","journal-title":"J. Mach. Learn. Res."},{"key":"ref22","first-page":"3111","article-title":"Distributed representations of words and phrases and their compositionality","volume-title":"Proc. 26th Int. Conf. Neural Inf. Process. Syst.","volume":"2","author":"Mikolov","year":"2013"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2021.10.009"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0096-5"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.03.009"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2113"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16164-1"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-022-01243-4"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aba1983"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.4096"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2015.11.006"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2015.85"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1101\/gr.1239303"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-022-02749-x"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-93484-2"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2022.154013"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27518"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2019.08.014"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11216421"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10582"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1002\/JLB.2MR0220-549R"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.4.2330"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-019-1114-y"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2021.12954"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2019-4965"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25270"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.844866"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02470-x"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055714"},{"key":"ref50","first-page":"4768","article-title":"A unified approach to interpreting model predictions","volume-title":"Proc. 31st Int. Conf. Neural Inf. Process. Syst.","author":"Lundberg","year":"2017"}],"container-title":["IEEE Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx8\/10723156\/11296745\/11129911.pdf?arnumber=11129911","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T12:27:33Z","timestamp":1766060853000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/11129911\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":50,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.1109\/tcbbio.2025.3600428","relation":{},"ISSN":["2998-4165"],"issn-type":[{"type":"electronic","value":"2998-4165"}],"subject":[],"published":{"date-parts":[[2025,11]]}}}