{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:21:23Z","timestamp":1769214083215,"version":"3.49.0"},"reference-count":85,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"8","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Med. Imaging"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1109\/tmi.2010.2047653","type":"journal-article","created":{"date-parts":[[2010,4,9]],"date-time":"2010-04-09T12:51:58Z","timestamp":1270817518000},"page":"1541-1559","source":"Crossref","is-referenced-by-count":64,"title":["Anatomically Corresponded Regional Analysis of Cartilage in Asymptomatic and Osteoarthritic Knees by Statistical Shape Modelling of the Bone"],"prefix":"10.1109","volume":"29","author":[{"given":"T G","family":"Williams","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A P","family":"Holmes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J C","family":"Waterton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R A","family":"Maciewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C E","family":"Hutchinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R J","family":"Moots","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A F P","family":"Nash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C J","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.089904"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2008.07.008"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1002\/art.11483"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.082107"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2008.05.013"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1002\/art.24208"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.04.007"},{"key":"ref39","year":"1998","journal-title":"Guidance for industry E6 good clinical practice Consolidated guidance"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.092221"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1109\/ISBI.2004.1398507"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1186\/ar2272"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1002\/art.23462"},{"key":"ref33","first-page":"51","article-title":"subdivision-based parametric deformable model for surface extraction and creation of 3-d statistical shape models of the knee cartilages","volume":"3765","author":"fripp","year":"2006","journal-title":"SPIE Med Imag"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2594(200001)43:1<126::AID-MRM15>3.0.CO;2-#"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2594(200010)44:4<592::AID-MRM13>3.0.CO;2-J"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S1063-4584(03)00091-8"},{"key":"ref37","first-page":"126","article-title":"corresponding articular cartilage thickness measurements in the knee joint by modelling the underlying bone","volume":"2732","author":"williams","year":"2003","journal-title":"IPMI 2003 Proc 18th Int Conf Inf Process Med Imag"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1002\/art.11259"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kei108"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.01.013"},{"key":"ref60","first-page":"29","author":"belle","year":"2002","journal-title":"Probability & Statistics"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/52\/6\/005"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8396(96)00031-3"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2007.08.002"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1117\/12.710152"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1007\/s004290000154"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1002\/art.20000"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2594(199903)41:3<529::AID-MRM15>3.3.CO;2-Q"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.076919"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2003.814539"},{"key":"ref67","author":"bowes","year":"2009","journal-title":"Reproducibility of MR Biomarkers of Cartilage Structure and Composition in an Osteoarthritis Population at Risk of Progression"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1016\/S1063-4584(09)60439-8"},{"key":"ref69","article-title":"measurement and visualisation of focal cartilage thickness change in small studies of knee osteoarthritis using a novel mr image analysis tool","author":"williams","year":"2009","journal-title":"Br J Radiol"},{"key":"ref2","year":"2003","journal-title":"The burden of musculoskeletal conditions at the start of the new millennium"},{"key":"ref1","year":"2002","journal-title":"Arthritis The big picture"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2005.04.001"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2005.04.013"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/00004424-199805000-00006"},{"key":"ref24","article-title":"subregional analysis of tibial cartilage changes in persons with knee osteoarthritis and malalignment","author":"eckstein","year":"2007","journal-title":"Proc ISMRM"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/S1063-4584(07)60702-X"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2007.907323"},{"key":"ref25","year":"2005","journal-title":"Method and system for automatic extraction of load-bearing regions of the cartilage and measurement of biomarkers"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2002.1009388"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1006\/cviu.1995.1004"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1007\/BF01774016"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1191\/096228099673819272"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/41\/9\/016"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2003.08.009"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1109\/34.927467"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1109\/34.121791"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/3-540-47977-5_1","article-title":"3-d statistical shape models using direct optimisation of description length","volume":"iii","author":"davies","year":"2002","journal-title":"ECCV 2002 7th European Conference on Computer Vision"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1006\/cviu.1995.1013"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1053\/joca.1998.0165"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/ard\/2003.007666"},{"key":"ref40","first-page":"1","article-title":"magnetic resonance imaging measurement of knee cartilage volume in a multi-centre study","volume":"42","author":"morgan","year":"2003","journal-title":"Rheumatology"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2005.04.009"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-861579"},{"key":"ref14","first-page":"283","article-title":"comparison of mri graded cartilage and mri based volume measurement in knee osteoarthritis","volume":"134","author":"baysal","year":"2004","journal-title":"Swiss Med Weekly"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.038869"},{"key":"ref82","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.088732"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2009.03.008"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1186\/ar2314"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.03.005"},{"key":"ref84","author":"balamoody","year":"2009","journal-title":"Intra- and Inter-Scanner Variability of Knee Cartilage T2 in Human Knees at 3 0T A Multivendor Comparison Study"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1117\/12.654164"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.03.017"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.039370"},{"key":"ref80","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.08.009"},{"key":"ref4","first-page":"8 8 1","volume":"2","author":"bullough","year":"1988","journal-title":"Rheumatology"},{"key":"ref3","first-page":"6","article-title":"the increasing impact of arthritis on public health","volume":"27","author":"elders","year":"2000","journal-title":"J Rheumatol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.02.026"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1693"},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-30136-3_116"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S1063-4584(03)00029-3"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1109\/42.52980"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1063"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.023069"},{"key":"ref46","author":"sethian","year":"1996","journal-title":"Level Set Methods Evolving Interfaces In Geometry Fluid Mechanics Computer Vision And Materials Science"},{"key":"ref45","article-title":"reconstruction of smooth surfaces with arbitrary topology adaptive splines","author":"stoddart","year":"1998","journal-title":"5th Eur Conf Comput Vis"},{"key":"ref48","author":"geiger","year":"1993","journal-title":"Three-dimensional modeling of human organs and its application to diagnosis and surgical planning"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1142\/S0129167X9600044X"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1147\/sj.351.0004"},{"key":"ref41","author":"nevitt","year":"2006","journal-title":"The osteoarthritis initiative protocol for the cohort study"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1115\/1.2895499"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1145\/321607.321609"}],"container-title":["IEEE Transactions on Medical Imaging"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx5\/42\/5532090\/05444989.pdf?arnumber=5444989","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T00:44:12Z","timestamp":1633913052000},"score":1,"resource":{"primary":{"URL":"http:\/\/ieeexplore.ieee.org\/document\/5444989\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":85,"journal-issue":{"issue":"8"},"URL":"https:\/\/doi.org\/10.1109\/tmi.2010.2047653","relation":{},"ISSN":["0278-0062","1558-254X"],"issn-type":[{"value":"0278-0062","type":"print"},{"value":"1558-254X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}