{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T04:00:27Z","timestamp":1772769627281,"version":"3.50.1"},"reference-count":36,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"}],"funder":[{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["DMR-106-157"],"award-info":[{"award-number":["DMR-106-157"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002836","name":"Institute for Radiological Research of Chang Gung University\/Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CIRPD1E0042"],"award-info":[{"award-number":["CIRPD1E0042"]}],"id":[{"id":"10.13039\/501100002836","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Med. Imaging"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1109\/tmi.2016.2646698","type":"journal-article","created":{"date-parts":[[2016,12,30]],"date-time":"2016-12-30T14:21:05Z","timestamp":1483107665000},"page":"1094-1105","source":"Crossref","is-referenced-by-count":21,"title":["A Novel Two-Compartment Model for Calculating Bone Volume Fractions and Bone Mineral Densities From Computed Tomography Images"],"prefix":"10.1109","volume":"36","author":[{"given":"Hsin-Hon","family":"Lin","sequence":"first","affiliation":[]},{"given":"Shin-Lei","family":"Peng","sequence":"additional","affiliation":[]},{"given":"Jay","family":"Wu","sequence":"additional","affiliation":[]},{"given":"Tian-Yu","family":"Shih","sequence":"additional","affiliation":[]},{"given":"Keh-Shih","family":"Chuang","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8554-9136","authenticated-orcid":false,"given":"Cheng-Ting","family":"Shih","sequence":"additional","affiliation":[]}],"member":"263","reference":[{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1111\/jmi.12159"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(02)00782-2"},{"key":"ref31","first-page":"23","article-title":"A threshold selection method from gray-level histograms","volume":"11","author":"otsu","year":"1975","journal-title":"Automatica"},{"key":"ref30","first-page":"235","article-title":"Proposal for shared collections of X-ray micro-CT datasets of bone specimens","author":"perilli","year":"2003","journal-title":"Proc Int Conf Comput Bioeng"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(99)00098-8"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1118\/1.597953"},{"key":"ref34","author":"berger","year":"2005","journal-title":"XCOM Photon Cross Sections Database NIST Standard Reference Database 8 (XGAM)"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2003.10.001"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/BF01774010"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-008-9174-x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.04.074"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-64-760-298"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650110218"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1118\/1.3005598"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-1258"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2006.06.013"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-010-1766-x"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1118\/1.596862"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-12-1016"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1080\/14786440509463378"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1093\/ajcn\/53.1.132","article-title":"Bone density in premenopausal women: Effects of age, dietary intake, physical activity, smoking, and birth-control pills","volume":"53","author":"mazess","year":"1991","journal-title":"Amer J Clin Nutrition"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1001\/jama.285.6.785","article-title":"Osteoporosis prevention, diagnosis, and therapy","volume":"285","author":"klibanski","year":"2001","journal-title":"J Amer Med Assoc"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-50-599-814"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","article-title":"Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women’s Health Initiative randomized controlled trial","volume":"288","author":"rossouw","year":"2002","journal-title":"J Amer Med Assoc"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/BF02556569"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-55-652-277"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08657-9"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1385\/JCD:3:4:373"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01622200"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2008.11.028"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-007-9021-5"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2010.04.023"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1998.13.1.122"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s001980050070"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-008-0820-y"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1359\/JBMR.050610"}],"container-title":["IEEE Transactions on Medical Imaging"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/42\/7915815\/07802550.pdf?arnumber=7802550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T11:40:35Z","timestamp":1641987635000},"score":1,"resource":{"primary":{"URL":"http:\/\/ieeexplore.ieee.org\/document\/7802550\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":36,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.1109\/tmi.2016.2646698","relation":{},"ISSN":["0278-0062","1558-254X"],"issn-type":[{"value":"0278-0062","type":"print"},{"value":"1558-254X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5]]}}}