{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T17:28:30Z","timestamp":1781717310765,"version":"3.54.5"},"reference-count":59,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"9","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Zhejiang Provincial Natural Science Foundation of China","doi-asserted-by":"publisher","award":["LZ19F010001"],"award-info":[{"award-number":["LZ19F010001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Key Research and Development Program of Zhejiang Province","award":["2020C030360"],"award-info":[{"award-number":["2020C030360"]}]},{"DOI":"10.13039\/501100001809","name":"National Science Foundation Program of China","doi-asserted-by":"publisher","award":["61906181"],"award-info":[{"award-number":["61906181"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2019M652156"],"award-info":[{"award-number":["2019M652156"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ningbo 2025 S&T Megaprojects","award":["2019B10033"],"award-info":[{"award-number":["2019B10033"]}]},{"name":"Ningbo 2025 S&T Megaprojects","award":["2019B10061"],"award-info":[{"award-number":["2019B10061"]}]},{"DOI":"10.13039\/100007834","name":"Ningbo Natural Science Foundation","doi-asserted-by":"publisher","award":["2018A610055"],"award-info":[{"award-number":["2018A610055"]}],"id":[{"id":"10.13039\/100007834","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Med. Imaging"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1109\/tmi.2020.2974499","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T20:28:41Z","timestamp":1581971321000},"page":"2725-2737","source":"Crossref","is-referenced-by-count":42,"title":["Automated Tortuosity Analysis of Nerve Fibers in Corneal Confocal Microscopy"],"prefix":"10.1109","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4357-4592","authenticated-orcid":false,"given":"Yitian","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1922-9118","authenticated-orcid":false,"given":"Jiong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7273-3295","authenticated-orcid":false,"given":"Ella","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7873-0922","authenticated-orcid":false,"given":"Yalin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7133-3863","authenticated-orcid":false,"given":"Pan","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianyang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3466-4302","authenticated-orcid":false,"given":"Yonggang","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6281-6505","authenticated-orcid":false,"given":"Jiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3774-2134","authenticated-orcid":false,"given":"Yonghuai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1007\/s10851-013-0488-6"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1007\/s11263-009-0213-5"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1137\/080725891"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1109\/TIP.2018.2810539"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1109\/TIP.2015.2474701"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s00500-017-2813-2"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122332"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022314423998"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1186\/s13638-017-0989-x"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1007\/s10915-018-0757-z"},{"key":"ref28","first-page":"230","article-title":"A retinex theory based points sampling method for mesh simplification","author":"zhao","year":"2011","journal-title":"Proc ISPA"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucom.2016.01.012"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1109\/ICSIPR.2013.6497976"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/cxo.12640"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.12466"},{"key":"ref20","first-page":"181","article-title":"ADRIS: An automatic diabetic retinal image screening system","volume":"60","author":"goh","year":"2001","journal-title":"Stud Fuzziness Soft Comput"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/S1386-5056(98)00163-4"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.patcog.2012.09.017"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1364\/JOSA.61.000001"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2017.2756073"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.sigpro.2008.01.028"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/11408031_19"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1109\/83.557356"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1109\/ICIP.2009.5414428"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-32245-8_16"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-32251-9_59"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07619-7"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-018-5695-5"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-32239-7_80"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1109\/CVPR.2016.304"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1109\/TPAMI.2012.213"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1109\/TCE.2007.381734"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-2114"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2016.2593725"},{"key":"ref40","first-page":"113","article-title":"Curvature based biomarkers for diabetic retinopathy via exponential curve fits in SE(2)","author":"bekkers","year":"2017","journal-title":"Proc MICCAI"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2019.2926492"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.17077\/omia.1016"},{"key":"ref14","first-page":"109","article-title":"Uniqueness-driven saliency analysis for automated abnormalities detection with application to retinal diseases","author":"zhao","year":"2018","journal-title":"Proc MICCAI"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1109\/CVPR.2019.00870"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2003.816964"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-67561-9_25"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/BF02150097"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159\/000158993"},{"key":"ref4","first-page":"56","article-title":"Retinal artery and vein classification via dominant sets clustering-based vascular topology estimation","author":"zhao","year":"2018","journal-title":"Proc MICCAI"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2016.04.006"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-32251-9_2"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-05023-4"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2007.904657"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e31824ee8c9"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2015.2409024"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-7529"},{"key":"ref46","first-page":"1589","article-title":"Evaluation of tortuosity of eye blood vessels using the integral of square of derivative of curvature","author":"patasius","year":"2005","journal-title":"Proc EMBC"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1016\/j.patcog.2014.04.010"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200105000-00008"},{"key":"ref47","first-page":"1","article-title":"Image processing techniques for the quantication of atherosclerotic changes","author":"chandrinos","year":"1998","journal-title":"Proc 18th Medit Conf Med Biol Eng Comput"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1016\/S1361-8415(02)00058-0"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2016.2587062"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.03-0637"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4108"}],"container-title":["IEEE Transactions on Medical Imaging"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/42\/9181677\/09000832.pdf?arnumber=9000832","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T13:59:14Z","timestamp":1651067954000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/9000832\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":59,"journal-issue":{"issue":"9"},"URL":"https:\/\/doi.org\/10.1109\/tmi.2020.2974499","relation":{},"ISSN":["0278-0062","1558-254X"],"issn-type":[{"value":"0278-0062","type":"print"},{"value":"1558-254X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9]]}}}