{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T22:42:20Z","timestamp":1783982540014,"version":"3.55.0"},"reference-count":59,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"funder":[{"name":"Swiss National Science Foundation, Qu3D \u201cQuantum 3D Imaging at high speed and high resolution,\u201d","award":["20QT21_187716"],"award-info":[{"award-number":["20QT21_187716"]}]},{"name":"Swiss National Science Foundation, Qu3D \u201cQuantum 3D Imaging at high speed and high resolution,\u201d","award":["200021_166289"],"award-info":[{"award-number":["200021_166289"]}]},{"name":"Halcomb Fellowship in Medicine and Engineering through the University of Kentucky. The work of Guoqiang Yu was supported by the National Institutes of Health","award":["R01 EB028792"],"award-info":[{"award-number":["R01 EB028792"]}]},{"name":"Halcomb Fellowship in Medicine and Engineering through the University of Kentucky. The work of Guoqiang Yu was supported by the National Institutes of Health","award":["R01-HD101508"],"award-info":[{"award-number":["R01-HD101508"]}]},{"name":"Halcomb Fellowship in Medicine and Engineering through the University of Kentucky. The work of Guoqiang Yu was supported by the National Institutes of Health","award":["R21-HD091118"],"award-info":[{"award-number":["R21-HD091118"]}]},{"name":"Halcomb Fellowship in Medicine and Engineering through the University of Kentucky. The work of Guoqiang Yu was supported by the National Institutes of Health","award":["R21-NS114771"],"award-info":[{"award-number":["R21-NS114771"]}]},{"name":"Halcomb Fellowship in Medicine and Engineering through the University of Kentucky. The work of Guoqiang Yu was supported by the National Institutes of Health","award":["R41-NS122722"],"award-info":[{"award-number":["R41-NS122722"]}]},{"name":"Halcomb Fellowship in Medicine and Engineering through the University of Kentucky. The work of Guoqiang Yu was supported by the National Institutes of Health","award":["R42-MH135825"],"award-info":[{"award-number":["R42-MH135825"]}]},{"name":"Halcomb Fellowship in Medicine and Engineering through the University of Kentucky. The work of Guoqiang Yu was supported by the National Institutes of Health","award":["R56-NS117587"],"award-info":[{"award-number":["R56-NS117587"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Med. Imaging"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1109\/tmi.2024.3486084","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T17:26:48Z","timestamp":1729790808000},"page":"1206-1217","source":"Crossref","is-referenced-by-count":11,"title":["Time-Resolved Laser Speckle Contrast Imaging (TR-LSCI) of Cerebral Blood Flow"],"prefix":"10.1109","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8061-6304","authenticated-orcid":false,"given":"Faraneh","family":"Fathi","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5683-9866","authenticated-orcid":false,"given":"Siavash","family":"Mazdeyasna","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dara","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5260-9112","authenticated-orcid":false,"given":"Chong","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4689-990X","authenticated-orcid":false,"given":"Mehrana","family":"Mohtasebi","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2537-7838","authenticated-orcid":false,"given":"Xuhui","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3051-2888","authenticated-orcid":false,"given":"Samaneh","family":"Rabienia Haratbar","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8657-4413","authenticated-orcid":false,"given":"Mingjun","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Chen","sequence":"additional","affiliation":[{"name":"Biostatistics and Bioinformatics Shared Resource Facility, Markey Cancer Center, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arin","family":"Can Ulku","sequence":"additional","affiliation":[{"name":"School of Engineering, École Polytechnique Fédérale de Lausanne, Neuchâtel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Mos","sequence":"additional","affiliation":[{"name":"School of Engineering, École Polytechnique Fédérale de Lausanne, Neuchâtel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6636-6596","authenticated-orcid":false,"given":"Claudio","family":"Bruschini","sequence":"additional","affiliation":[{"name":"School of Engineering, École Polytechnique Fédérale de Lausanne, Neuchâtel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0620-3365","authenticated-orcid":false,"given":"Edoardo","family":"Charbon","sequence":"additional","affiliation":[{"name":"School of Engineering, École Polytechnique Fédérale de Lausanne, Neuchâtel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1218-8704","authenticated-orcid":false,"given":"Lei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Physiology, Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2900-6268","authenticated-orcid":false,"given":"Guoqiang","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Kentucky, Lexington, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.9.005719"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2007.04.015"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aem131"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-011-0469-0"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1117\/12.2610178"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1364\/OL.39.005006"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.07.037"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2016.10.100"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1364\/OL.34.003556"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.473992"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1063\/1.881445"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.441061"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6579\/aa60b7"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1364\/OE.14.001125"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1364\/OE.26.000963"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.95.078101"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.4.002893"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.05.106"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1364\/OPTICA.3.001006"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1117\/12.2527160"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1109\/CICC.2019.8780320"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.418882"},{"key":"ref23","volume-title":"Multi-wavelength time-resolved laser speckle contrast imaging (MTR-LSCI) of tissue hemodynamics and metabolism","author":"Yu","year":"2023"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.25.9.097003"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1109\/TED.2015.2458295"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/s41377-019-0191-5"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1109\/JSTQE.2018.2867439"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.05.047"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.26.1.012705"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1117\/1.NPh.10.4.045007"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.4.001883"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1364\/OE.22.017573"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1109\/ICCPHOT.2019.8747325"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1364\/OPTICA.386574"},{"key":"ref35","volume-title":"Large-format time-gated SPAD cameras for real-time phasor-based FLIM","author":"\u00dclk\u00fc","year":"2021"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1109\/TED.2022.3168249"},{"key":"ref37","article-title":"Time-resolved laser speckle contrast imaging (TR-LSCI) of cerebral blood flow","author":"Fathi","year":"2023","journal-title":"arXiv:2309.13527"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1117\/12.2609939"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1088\/2050-6120\/ab6ed7"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1117\/1.3285504"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.10.9.19"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1117\/1.NPh.3.3.031412"},{"key":"ref43","volume-title":"Mathworks","year":"2024"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/414682"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2011.08.001"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.00172"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1364\/OPTICA.431521"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1117\/1.3149863"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1201\/b10951-14"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-81448-5"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.28.12.125002"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1109\/RBME.2016.2532598"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1117\/1.NPh.6.3.035001"},{"key":"ref54","volume-title":"SPAD512S","year":"2023"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1364\/OE.488177"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2014.211"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1117\/12.2609144"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.28.12.121204"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1364\/OL.38.003690"}],"container-title":["IEEE Transactions on Medical Imaging"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx8\/42\/10930313\/10734408.pdf?arnumber=10734408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T17:37:54Z","timestamp":1742319474000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/10734408\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":59,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1109\/tmi.2024.3486084","relation":{},"ISSN":["0278-0062","1558-254X"],"issn-type":[{"value":"0278-0062","type":"print"},{"value":"1558-254X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3]]}}}