{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T09:28:07Z","timestamp":1770542887793,"version":"3.49.0"},"reference-count":63,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Visual. Comput. Graphics"],"published-print":{"date-parts":[[2022]]},"DOI":"10.1109\/tvcg.2022.3209434","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T19:49:08Z","timestamp":1664308148000},"page":"1-11","source":"Crossref","is-referenced-by-count":6,"title":["MedChemLens: An Interactive Visual Tool to Support Direction Selection in Interdisciplinary Experimental Research of Medicinal Chemistry"],"prefix":"10.1109","author":[{"given":"Chuhan","family":"Shi","sequence":"first","affiliation":[{"name":"Hong Kong University of Science and Technology, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Nie","sequence":"additional","affiliation":[{"name":"Hong Kong University of Science and Technology, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yicheng","family":"Hu","sequence":"additional","affiliation":[{"name":"Hong Kong University of Science and Technology, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yige","family":"Xu","sequence":"additional","affiliation":[{"name":"Nanyang Technological University, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8257-5806","authenticated-orcid":false,"given":"Lei","family":"Chen","sequence":"additional","affiliation":[{"name":"Hong Kong University of Science and Technology, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9847-7784","authenticated-orcid":false,"given":"Xiaojuan","family":"Ma","sequence":"additional","affiliation":[{"name":"Hong Kong University of Science and Technology, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4275-1756","authenticated-orcid":false,"given":"Qiong","family":"Luo","sequence":"additional","affiliation":[{"name":"Hong Kong University of Science and Technology, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"263","reference":[{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1072"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky1075"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1055"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1038\/nrd986"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv951"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-417205-0.00001-8"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2018.11.002"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1145\/1056808.1057069"},{"key":"ref35","author":"landrum","year":"2013","journal-title":"Rdkit A software suite for cheminformatics computational chemistry and predictive modeling"},{"key":"ref34","first-page":"225","article-title":"9. the essential tension: Tradition and innovation in scientific research","author":"kuhn","year":"2011","journal-title":"The Essential Tension"},{"key":"ref60","first-page":"1332","article-title":"A method to accelerate and visualize iterative clinical paper searching","author":"yu","year":"2019","journal-title":"MEDINFO 2019 Health and Wellbeing e-Networks for All"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2013.167"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2009.202"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2012.277"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1145\/3411764.3445674"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2015.2467621"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-90872-4"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/medsci6020043"},{"key":"ref1","author":"abbott","year":"2018","journal-title":"Research Design and Methods A Process Approach"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1057\/palgrave.ivs.9500156"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.8b00359"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113333"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.14682"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2012.324"},{"key":"ref26","article-title":"Clinical safety data management: definitions and standards for expedited reporting e2a","year":"0","journal-title":"International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1145\/2089094.2089099"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1060d","DOI":"10.1093\/nar\/gkq1037","article-title":"Promiscuous: a database for network-based drug-repositioning","volume":"39","author":"von eichborn","year":"2010","journal-title":"Nucleic Acids Research"},{"key":"ref51","article-title":"The TREC-8 question answering track","author":"voorhees","year":"2000","journal-title":"Proceedings of the Second International Conference on Language Resources and Evaluation (LREC'00)"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1007\/s10822-016-9915-2"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku337"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.9b00359"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1021\/ci00057a005"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1162\/tacl_a_00290"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2016.2515592"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113381"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1016\/j.joi.2010.06.004"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1109\/VAST.2014.7042511"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-41335-3_29"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2013.212"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/wics.1310"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1109\/IV.2011.95"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2017.36"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1109\/iV.2018.00033"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.18653\/v1\/N19-1423"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.13281"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2012.252"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/asi.22652"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.0c00042"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-6613-4_13"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1109\/VIS47514.2020.00052"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2015.2467757"},{"key":"ref8","volume":"72","author":"buschmann","year":"2018","journal-title":"Drug Selectivity An Evolving Concept in Medicinal Chemistry"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"9923e","DOI":"10.15252\/msb.20209923","article-title":"Integrated intra- and inter-cellular signaling knowledge for multicellular omics analysis","volume":"17","author":"t\u00fcrei","year":"2021","journal-title":"Molecular Systems Biology"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2016.2598667"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2021.3054916"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.11.135"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1021\/ci100050t"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2014.05.012"},{"key":"ref47","article-title":"Drug solubility: importance and enhancement techniques","author":"savjani","year":"2012","journal-title":"International Scholarly Research Notices"},{"key":"ref42","article-title":"Handbook of Cell Signaling","author":"ralph","year":"2004","journal-title":"Cell Biology"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2275"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-397176-0.00001-7"},{"key":"ref43","first-page":"89","article-title":"Modern drug discovery process: An in silico approach","volume":"3","author":"rao","year":"2011","journal-title":"Journal of Bioinformatics and Sequence Analysis"}],"container-title":["IEEE Transactions on Visualization and Computer Graphics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/2945\/4359476\/09904486.pdf?arnumber=9904486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T15:56:12Z","timestamp":1671465372000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/9904486\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":63,"URL":"https:\/\/doi.org\/10.1109\/tvcg.2022.3209434","relation":{},"ISSN":["1077-2626","1941-0506","2160-9306"],"issn-type":[{"value":"1077-2626","type":"print"},{"value":"1941-0506","type":"electronic"},{"value":"2160-9306","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}