{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:28:13Z","timestamp":1790890093245,"version":"4.1.0"},"reference-count":25,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"3","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE\/ACM Trans. Comput. Biol. and Bioinf."],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1109\/tcbb.2004.24","type":"journal-article","created":{"date-parts":[[2005,1,12]],"date-time":"2005-01-12T19:16:30Z","timestamp":1105557390000},"page":"98-108","source":"Crossref","is-referenced-by-count":26,"title":["A stochastic downhill search algorithm for estimating the local false discovery rate"],"prefix":"10.1109","volume":"1","author":[{"given":"S.","family":"Scheid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Spang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref1","article-title":"Microarray Suite User\u2019s Guide","volume-title":"Affymetrix Inc.","year":"2001"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-9473(01)00046-9"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1214\/aos\/1013699998"},{"key":"ref5","article-title":"A Bayesian Mixture Model for Differential Gene Expression","author":"Do","year":"2003"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1214\/ss\/1056397487"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1198\/016214501753382129"},{"issue":"4","key":"ref8","article-title":"Estimating the Proportion of True Null Hypotheses, with Application to DNA Microarray Data","volume-title":"Preprint Series in Statistics","author":"Ferkingstad","year":"2003"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/1521-4036(200112)43:8<985::AID-BIMJ985>3.0.CO;2-4"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780198526155.003.0008"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1214\/009053604000000283"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/18.suppl_1.S96"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gng015"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bth310"},{"key":"ref15","article-title":"User\u2019s Guide to BUM Library Version 1-1","author":"Pounds","year":"2003"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bth160"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btg148"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btf877"},{"key":"ref19","article-title":"A False Discovery Rate Approach to Separate the Score Distributions of Induced and Noninduced Genes","volume-title":"Proc. Third Int\u2019l Workshop Distributed Statistical Computing","author":"Scheid"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1385\/1-59259-364-X:111"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1214\/aos\/1074290335"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1530509100"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.0006-341X.2003.00123.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.091062498"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(02)00032-6"}],"container-title":["IEEE\/ACM Transactions on Computational Biology and Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx5\/8857\/30055\/01377138.pdf?arnumber=1377138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T04:39:22Z","timestamp":1742186362000},"score":1,"resource":{"primary":{"URL":"http:\/\/ieeexplore.ieee.org\/document\/1377138\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,7]]}},"URL":"https:\/\/doi.org\/10.1109\/tcbb.2004.24","relation":{},"ISSN":["1545-5963"],"issn-type":[{"value":"1545-5963","type":"print"}],"subject":[],"published":{"date-parts":[[2004,7]]}}}