{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T22:14:25Z","timestamp":1784240065822,"version":"3.55.0"},"reference-count":80,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"6","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE\/ACM Trans. Comput. Biol. and Bioinf."],"published-print":{"date-parts":[[2019,11,1]]},"DOI":"10.1109\/tcbb.2018.2835459","type":"journal-article","created":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T15:04:39Z","timestamp":1526569479000},"page":"1830-1842","source":"Crossref","is-referenced-by-count":8,"title":["A Parametric Targetability Evaluation Approach for Vitiligo Proteome Extracted through Integration of Gene Ontologies and Protein Interaction Topologies"],"prefix":"10.1109","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7204-2504","authenticated-orcid":false,"given":"Anvita Gupta","family":"Malhotra","sequence":"first","affiliation":[{"name":"Maulana Azad National Institute of Technology, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudha","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Biological Science and Engineering, Maulana Azad National Institute of Technology, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Jha","sequence":"additional","affiliation":[{"name":"Department of Biological Science and Engineering, Maulana Azad National Institute of Technology, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khushhali M.","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Biological Science and Engineering, Maulana Azad National Institute of Technology, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref73","article-title":"Heteroaryl urea derivatives useful for inhibiting CHK1","author":"diaz","year":"2012"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/S0026-895X(25)09702-0","article-title":"Inhibition of epidermal growth factor receptor tyrosine kinase activity in A431 human epidermoid cells following psoralen\/ultraviolet light treatment","volume":"36","author":"mermelstein","year":"1989","journal-title":"Molecular Pharmacology"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12100"},{"key":"ref70","article-title":"Treatment of sirtuin (sirt) related diseases by inhibition of natural antisense transcript to a sirtuin (sirt)","author":"collard","year":"2015"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15151"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2016.06.031"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts251"},{"key":"ref74","article-title":"Compounds Useful for Inhibiting Chk1","author":"gaudino","year":"2008"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1038\/srep16830"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.1097\/PAI.0b013e318246c793"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.1520"},{"key":"ref79","article-title":"Treatment for vitiligo","author":"magilavy","year":"2017"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt533"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr1088"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp983"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw937"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm554"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1007\/s12539-017-0213-z"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1102"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq1167"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.65.056109"},{"key":"ref62","article-title":"The igraph software package for complex network research","volume":"1695","author":"csardi","year":"2006","journal-title":"InterJ Complex Syst"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1038\/35019019"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"535d","DOI":"10.1093\/nar\/gkj109","article-title":"BioGRID: a general repository for interaction datasets","volume":"34","author":"stark","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.2174\/157016307781115494"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/database\/bav028"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2918"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0701361104"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/30.1.303"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201100346"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.03.020"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.06.029"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.12206"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-6-3"},{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.11"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2014.08.008"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-017-3510-3"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-015-1128-6"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2011.09.007"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn982"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1093\/database\/baw100"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2015.00366"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2008.08.001"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr986"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1186\/1745-7580-4-4"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1007\/s10969-012-9133-7"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv1072"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiotec.2017.04.020"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl940"},{"key":"ref54","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2005-6-9-119","article-title":"The mammalian phenotype ontology as a tool for annotating, analyzing and comparing phenotypic information","volume":"6","author":"smith","year":"2005","journal-title":"Genome Biol"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1071"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003484"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.2006.00333.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2002.1o049.x"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1338"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2003.00070.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.1993.tb00023.x"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1600-0625.2007.00666.x","article-title":"Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?","volume":"17","author":"schallreuter","year":"2008","journal-title":"Experimental Dermatology"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.328"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002819"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.artmed.2014.03.003"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.artmed.2011.09.003"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.patbio.2008.10.004"},{"key":"ref80","article-title":"Gsk3b and uses thereof in the diagnostic and treatment of hypopigmentation disorders","author":"passeron","year":"2017"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.01139.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/1721727X0600400103"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2003.00023.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60763-7"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2000.130106.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.2004.00130.x"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2689"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3680"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(00)00129-0"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-9-104"},{"key":"ref48","article-title":"Proteomics. Tissue-based map of the human proteome","volume":"347","author":"uhlen","year":"2015","journal-title":"Sci"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.1.235"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1182"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbv059"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1068"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.15406\/mojpb.2015.02.00050"}],"container-title":["IEEE\/ACM Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx7\/8857\/8929069\/08360556.pdf?arnumber=8360556","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T21:51:00Z","timestamp":1784238660000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/8360556\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,1]]},"references-count":80,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.1109\/tcbb.2018.2835459","relation":{},"ISSN":["1545-5963","1557-9964","2374-0043"],"issn-type":[{"value":"1545-5963","type":"print"},{"value":"1557-9964","type":"electronic"},{"value":"2374-0043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,1]]}}}