{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:45:22Z","timestamp":1791873922634,"version":"4.3.4"},"reference-count":43,"publisher":"Institute of Electrical and Electronics Engineers (IEEE)","issue":"5","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/downloads\/license-information\/IEEE.html"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/ieeexplore.ieee.org\/Xplorehelp\/tdmrep.html"}],"funder":[{"name":"National Science Foundation of China","award":["62306011"],"award-info":[{"award-number":["62306011"]}]},{"name":"Key Scientific Research Foundation of Education Department of Anhui Province","award":["2023AH050631"],"award-info":[{"award-number":["2023AH050631"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IEEE Trans. Comput. Biol. Bioinform."],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1109\/tcbbio.2026.3724882","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T19:15:14Z","timestamp":1787080514000},"page":"2208-2221","source":"Crossref","is-referenced-by-count":0,"title":["LOGIC: LLM-Driven Cross-Scale Feature Coupling for Drug-Disease Interaction Prediction"],"prefix":"10.1109","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7855-6808","authenticated-orcid":false,"given":"Yunfei","family":"He","sequence":"first","affiliation":[{"name":"Anhui Medical University","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1335-1357","authenticated-orcid":false,"given":"Shikai","family":"Chen","sequence":"additional","affiliation":[{"name":"Anhui Medical University","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3654-6613","authenticated-orcid":false,"given":"Yuchen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Anhui Medical University","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1450-4385","authenticated-orcid":false,"given":"Jingmiao","family":"Xu","sequence":"additional","affiliation":[{"name":"Anhui Medical University","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3285-0266","authenticated-orcid":false,"given":"Jie","family":"Ren","sequence":"additional","affiliation":[{"name":"Anhui Medical University","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2440-5961","authenticated-orcid":false,"given":"Yuling","family":"Li","sequence":"additional","affiliation":[{"name":"Anhui Medical University","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8784-5693","authenticated-orcid":false,"given":"Fei","family":"Yang","sequence":"additional","affiliation":[{"name":"Anhui Medical University","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8709-1088","authenticated-orcid":false,"given":"Yiwen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Anhui University","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"263","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114239"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s11704-024-40072-y"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2019.2933825"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.1434"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2021.10.010"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s12257-020-0049-y"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/minf.202100200"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-95933-7_48"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/electronics13193835"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1205144"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-020-00456-1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1109\/BIBM66473.2025.11356739"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.5c00435"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37098-4"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e39038"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1021\/ci980159j"},{"key":"ref17","article-title":"Smiles transformer: Pre-trained molecular fingerprint for low data drug discovery","author":"Honda","year":"2019"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbad422"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2011.26"},{"key":"ref20","article-title":"DeepSeek-R1: Incentivizing reasoning capability in LLMs via reinforcement learning","author":"Guo","year":"2025"},{"key":"ref21","article-title":"Qwen technical report","author":"Bai","year":"2023"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw228"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx1037"},{"issue":"3","key":"ref24","article-title":"Medical subject headings (MeSH)","volume":"88","author":"Lipscomb","year":"2000","journal-title":"Bull. Med. Library Assoc."},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1002\/cpbi.27"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbab581"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbab319"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btad748"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1109\/JBHI.2024.3372527"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2023.3292883"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-025-06783-x"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1109\/TCBBIO.2025.3636508"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01296-0"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-03502-3"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkae300"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-018-2220-4"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2022.3144429"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1109\/TCBB.2024.3486216"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1109\/TCBBIO.2025.3593469"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1016\/j.artmed.2024.102805"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1609\/aaai.v38i9.28887"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1109\/BIBM62325.2024.10822460"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1016\/j.knosys.2023.111329"}],"container-title":["IEEE Transactions on Computational Biology and Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx8\/10723156\/11732242\/11657908.pdf?arnumber=11657908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:52:57Z","timestamp":1791870777000},"score":1,"resource":{"primary":{"URL":"https:\/\/ieeexplore.ieee.org\/document\/11657908\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":43,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.1109\/tcbbio.2026.3724882","relation":{},"ISSN":["2998-4165"],"issn-type":[{"value":"2998-4165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]}}}