{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:24:51Z","timestamp":1780482291872,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T00:00:00Z","timestamp":1354752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Several skin diseases are believed to be associated with oxidative stress. Tinea pedis is an infection of the feet caused by fungi. The infectious diseases caused by dermatophytes are mainly related to the enzymes produced by these fungi. The cutaneous oxidative stress status of tinea pedis has not been demonstrated in the published work up to now. The aim of the present study was to evaluate the role of oxidative stress in affected skin areas in a group of patients with interdigital tinea pedis. Thirty\u2010one consecutive patients with a diagnosis of unilateral interdigital tinea pedis were enrolled. The samples were obtained by scraping the skin surface. Oxidative stress biomarkers such as superoxide dismutase, catalase and malondialdehyde levels were measured spectrophotometrically. The activities of superoxide dismutase and catalase and the levels of malondialdehyde were significantly higher on the lesional area than the non\u2010lesional area (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). According to sex and fungal subtypes, there was no significant difference in the levels of oxidative stress biomarkers in patients with tinea pedis (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). Our results suggested that antioxidant defense of lesional skin surface was higher compared to non\u2010lesional skin. This is possibly due to a compensatory response to various fungal infections and thereby protects the cells against oxidative damage.<\/jats:p>","DOI":"10.1111\/1346-8138.12043","type":"journal-article","created":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T09:46:46Z","timestamp":1354787206000},"page":"114-117","source":"Crossref","is-referenced-by-count":10,"title":["Local oxidative stress in interdigital tinea pedis"],"prefix":"10.1111","volume":"40","author":[{"given":"Perihan","family":"Ozturk","sequence":"first","affiliation":[{"name":"Department of Dermatology  Faculty of Medicine Kahramanmaras Sutcu Imam University Kahramanmaras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozer","family":"Arican","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Trakya University Edirne Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ergul B.","family":"Kurutas","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Medicine Kahramanmaras Sutcu Imam University Kahramanmaras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tugba","family":"Karakas","sequence":"additional","affiliation":[{"name":"Department of Dermatology  Faculty of Medicine Kahramanmaras Sutcu Imam University Kahramanmaras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meltem","family":"Gungor","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Medicine Kahramanmaras Sutcu Imam University Kahramanmaras"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00580-008-0798-z"},{"key":"e_1_2_6_3_1","first-page":"192","article-title":"Comparation of combined clotrimasol and aluminium hydroxycloride with clotrimasol terapy in interdigital type tinea pedis","volume":"18","author":"Koca R","year":"2001","journal-title":"OMU Tip Derg"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-008-9104-5"},{"key":"e_1_2_6_5_1","first-page":"137","article-title":"Investigation of protease activities of Trichophyton rubrum and Trichophyton mentagrophytes obtained from clinical isolates","volume":"23","author":"Tanis H","year":"2009","journal-title":"FU Sag Bil Tip Derg"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-008-9110-7"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1128\/CMR.8.3.317","article-title":"Wagnerandpeter GS. 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