{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:38:04Z","timestamp":1789785484995,"version":"4.0.1"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,2,18]],"date-time":"2013-02-18T00:00:00Z","timestamp":1361145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The terminology and classification of keratoacanthoma (<jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content>) and other types of squamous cell carcinoma (<jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>) with crateriform architecture have not been clarified. The study evaluated the clinicopathological features of 41 nodular (exo\u2010endophytic) <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> lesions with a central keratin\u2010filled crater, including <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content> (well\u2010developed stage). The lesions were histopathologically classified into six categories: (i) <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content> (well\u2010developed stage) (27 lesions); (ii) <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content>\u2010like <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> (three lesions); (iii) <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content> with malignant transformation (three lesions); (iv) infundibular <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> (crateriform) (four lesions); (v) crateriform <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> arisen from actinic keratosis (three lesions); and (vi) crateriform Bowen's disease (one lesion). The true characteristics of <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content>\u2010like <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> remain unresolved, but there are three possibilities, namely, that it is one step in the evolution of <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content>, it is a borderline lesion between <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content> and invasive <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>, or it is one form of \u201c<jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content> with malignant transformation\u201d. <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> KA<\/jats:styled-content>\u2010like <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> KA<\/jats:styled-content> with malignant transformation and infundibular <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> (crater form) are considered to be hair follicle\u2010related neoplasms. In contrast, crateriform <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> arisen from actinic keratosis and crateriform Bowen's disease are <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>, which are not related either to the hair follicles or <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content>. From an etiological standpoint, the presented lesions in these six categories are considered to be mixed up due to the similarity of crateriform architecture between the various types of lesions. However, the information provided in this report is intended to help physicians to make an accurate differential diagnosis of these conditions in clinical practice. The present study provides an opportunity to standardize the terminology for <jats:styled-content style=\"fixed-case\">KA<\/jats:styled-content> and related neoplasms.<\/jats:p>","DOI":"10.1111\/1346-8138.12104","type":"journal-article","created":{"date-parts":[[2013,2,18]],"date-time":"2013-02-18T22:48:11Z","timestamp":1361227691000},"page":"443-452","source":"Crossref","is-referenced-by-count":39,"title":["Keratoacanthoma and other types of squamous cell carcinoma with crateriform architecture: Classification and identification"],"prefix":"10.1111","volume":"40","author":[{"given":"Noriyuki","family":"Misago","sequence":"first","affiliation":[{"name":"Division of Dermatology Department of Internal Medicine Faculty of Medicine Saga University Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Inoue","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Internal Medicine Faculty of Medicine Saga University Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Koba","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Internal Medicine Faculty of Medicine Saga University Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Narisawa","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Internal Medicine Faculty of Medicine Saga University Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,18]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1979.tb03568.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)80010-9"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2009.06.010"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199308000-00007"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70001-X"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30080.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00125480-199809000-00001"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03260.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2004.0150a.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2007.00764.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2008.03.001"},{"key":"e_1_2_5_13_1","volume-title":"Neoplasms With Follicular Differentiation","author":"Ackerman AB","year":"2001"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200008000-00002"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181c4340a"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2009.09.003"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2003.0150b.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.114"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2009.01286.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/jd.1999.v40.a94419"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2004.05.007"},{"key":"e_1_2_5_22_1","article-title":"Recurrent keratoacanthomas developing after spontaneous resolution","author":"Misago N","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70180-2"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.104"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30086.x"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.4823"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200204000-00012"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(69)91590-6"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197205)29:5<1387::AID-CNCR2820290541>3.0.CO;2-K"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1980.tb01202.x"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2008.07042"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2011.09.004"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e318205b2c5"},{"key":"e_1_2_5_34_1","unstructured":"AckermanAB.Interactive Quizzes Quiz 319 Squamous\u2010cell carcinoma keratoacanthomatous and solar keratotic in continuity with solar keratosis. 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