{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:39:47Z","timestamp":1787013587710,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T00:00:00Z","timestamp":1371427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Certain autoimmune bullous diseases (\n                    <jats:styled-content style=\"fixed-case\">AIBD<\/jats:styled-content>\n                    ), including pemphigoid and pemphigus, confer increased infection risk. Infections have not been systematically studied in these conditions, however. Little is known about infection risk in these conditions, particularly dermatitis herpetiformis (DH). We aimed to characterize and compare infection patterns and risk factors in patients with pemphigoid, pemphigus, and DH. We retrospectively studied the medical records of Olmsted County, Minnesota, residents who had a diagnosis of\n                    <jats:styled-content style=\"fixed-case\">AIBD<\/jats:styled-content>\n                    between 1\u00a0January 1998 and 1\u00a0January 2011. Of 81 patients studied, 54 (67%) had pemphigoid, 11 (14%) had pemphigus and 16 (20%) had\n                    <jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content>\n                    . Most patients studied developed at least one localized infection (72%) or one systemic infection (83%). Almost one\u2010third of patients (31%) developed infections requiring hospitalization or contributing to death. All patients taking systemic corticosteroids experienced a localized or systemic infection during the follow\u2010up period. Systemic infections were significantly less frequent in patients with\n                    <jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content>\n                    than those with pemphigoid or pemphigus (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\u00a00.03), as were systemic infections requiring hospitalization or contributing to death (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\u00a00.002). Patients with\n                    <jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content>\n                    were significantly less likely to require systemic corticosteroids (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.001) and significantly more likely to receive dapsone (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\u00a00.002). The study design was retrospective and a limited number of patients met the inclusion criteria. Patients with\n                    <jats:styled-content style=\"fixed-case\">AIBD<\/jats:styled-content>\n                    frequently developed localized and systemic infections, a substantial portion of which contributed to hospitalization or death. Patients with\n                    <jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content>\n                    experienced infections of lesser severity than patients with pemphigoid or pemphigus.\n                  <\/jats:p>","DOI":"10.1111\/1346-8138.12175","type":"journal-article","created":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T01:52:53Z","timestamp":1371433973000},"page":"613-619","source":"Crossref","is-referenced-by-count":29,"title":["Infection in autoimmune bullous diseases: A retrospective comparative study"],"prefix":"10.1111","volume":"40","author":[{"given":"Julia S.","family":"Lehman","sequence":"first","affiliation":[{"name":"Division of Dermatopathology and Cutaneous Immunopathology Department of Dermatology Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Khunger","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Lohse","sequence":"additional","affiliation":[{"name":"Division of Biomedical Statistics and Informatics Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1975.tb06488.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(82)70111-2"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2011.06.021"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2010.03.015"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09350.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.6.691"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2004.22504.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.23628.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2006.12.034"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.249"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1948.01520170134015"},{"key":"e_1_2_7_13_1","first-page":"436","article-title":"Dermatitis herpetiformis associated with a focus infection","volume":"9","author":"Coskey RJ","year":"1961","journal-title":"Henry Ford Hosp Med Bull"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.4065\/71.3.266"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1983.tb07687.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1996.tb02972.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1986.tb03431.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199812)19:6<446::AID-DC8>3.0.CO;2-2"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200809030-00004"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546630903287452"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e3181e59aac"},{"key":"e_1_2_7_22_1","first-page":"1","article-title":"Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"57","author":"Harpaz R","year":"2008","journal-title":"MMWR Recomm Rep"},{"issue":"2","key":"e_1_2_7_23_1","first-page":"1","article-title":"General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"60","author":"National Center for Immunization and Respiratory Diseases","year":"2011","journal-title":"MMWR Recomm Rep"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1995.tb03878.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03194.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.11.588"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114733"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00044067-200208000-00005"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2011.0012"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn489"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-2797(00)00072-7"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12175","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T11:27:30Z","timestamp":1696505250000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,17]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/1346-8138.12175"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12175","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,17]]}}}