{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T14:24:32Z","timestamp":1773325472917,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,6,3]],"date-time":"2013-06-03T00:00:00Z","timestamp":1370217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Beh\u00e7et's disease is a systemic inflammatory disorder with chronic remissions and relapses. Involvement of the central nervous system, called neuro\u2010<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>eh\u00e7et's disease (<jats:styled-content style=\"fixed-case\">NBD<\/jats:styled-content>), is a serious complication. Although corticosteroids and immunosuppressive agents are used, there is no definite standard of treatment with long term\u2010effects for <jats:styled-content style=\"fixed-case\">NBD<\/jats:styled-content>. Here, we report a female case with <jats:styled-content style=\"fixed-case\">NBD<\/jats:styled-content> successfully treated by infliximab and corticosteroids for 2\u00a0years. Our report suggests treatment with infliximab may be effective for long\u2010term remission of <jats:styled-content style=\"fixed-case\">NBD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/1346-8138.12203","type":"journal-article","created":{"date-parts":[[2013,6,3]],"date-time":"2013-06-03T11:44:21Z","timestamp":1370259861000},"page":"632-634","source":"Crossref","is-referenced-by-count":11,"title":["Case of neuro\u2010<scp>B<\/scp>eh\u00e7et's disease successfully maintained a remission using infliximab for 2\u00a0years"],"prefix":"10.1111","volume":"40","author":[{"given":"Hisashi","family":"Kanemaru","sequence":"first","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takamitsu","family":"Makino","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Jinnin","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Yonemitsu","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsunari","family":"Makino","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironobu","family":"Ihn","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,3]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.suppl_2.ii51"},{"key":"e_1_2_4_3_1","first-page":"S6","article-title":"Beh\u00e7et's disease: an update on the pathogenesis","volume":"19","author":"G\u00fcl A","year":"2001","journal-title":"Clin Exp Rheumatol"},{"issue":"1","key":"e_1_2_4_4_1","first-page":"128","article-title":"Systemic levels of the T cell regulatory cytokines IL\u201010 and IL\u201012 in Bech\u00e7et's disease; soluble TNFR\u201075 as a biological marker of disease activity","volume":"24","author":"Turan B","year":"1997","journal-title":"J Rheumatol"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/09629350220131935"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1997.274-ce1159.x"},{"key":"e_1_2_4_7_1","first-page":"1544","article-title":"Overproduction of monocyte derived tumor necrosis factor \u03b1, interleukin (IL) 6, IL\u20108 and increased neutrophil superoxide generation in Beh\u00e7et's disease. 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