{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T23:08:17Z","timestamp":1769123297874,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T00:00:00Z","timestamp":1388707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to investigate the efficacy of local injection of botulinum toxin A for treating axillary osmidrosis. One hundred and fifty patients with axillary osmidrosis were randomly divided to receive botulinum toxin A injection treatment (50\u00a0U of botulinum toxin A was injected intracutaneously into 6\u201320 different sites within each axilla, <jats:italic>n<\/jats:italic>\u00a0=\u00a074) or surgical excision of the apocrine glands (<jats:italic>n<\/jats:italic>\u00a0=\u00a076). The patients were followed up for 1\u20133\u00a0months to analyze the therapeutic effect and complications of the two methods. The curative effect in patients with mild and moderate axillary osmidrosis was not significantly different between the botulinum toxin A injection group and operation group. However, for patients with severe axillary osmidrosis, surgery treatment seemed to be superior to botulinum toxin A treatment (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005). There was also no significant difference in the modified Dermatology Life Quality Index between the two treatments. Two cases showed complications related to hemorrhage and incision infection in the operation group. In conclusion, local injection of botulinum toxin A is a safe, fast and effective treatment for mild and moderate axillary osmidrosis, but the long\u2010term effect remains to be further investigated.<\/jats:p>","DOI":"10.1111\/1346-8138.12230","type":"journal-article","created":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T13:08:07Z","timestamp":1388754487000},"page":"153-156","source":"Crossref","is-referenced-by-count":26,"title":["Local injection of botulinum toxin A: An alternative therapy for axillary osmidrosis"],"prefix":"10.1111","volume":"41","author":[{"given":"Aiguo","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery Second Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanjun","family":"Nie","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Second Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Affiliated Drum Tower Hospital of Nanjing University Medical School Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2003.11.001"},{"key":"e_1_2_7_3_1","first-page":"312","article-title":"Morphologic study of human apocrine sweat glands","volume":"28","author":"Wei CE","year":"2007","journal-title":"Med J Wuhan 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