{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T05:55:25Z","timestamp":1720072525278},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fibroblasts, mast cells and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>chwann cells were isolated from neurofibromas of patients with neurofibromatosis 1, and their responses to 308\u2010nm excimer light irradiation and\/or vitamin <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content><jats:sub>3<\/jats:sub> or an analog (tacalcitol; 1,24\u2010dihydroxyvitamin <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content><jats:sub>3<\/jats:sub>) were examined <jats:italic>in vitro<\/jats:italic>. Excimer light irradiation (300\u00a0mJ\/cm<jats:sup>2<\/jats:sup>) suppressed the growth of all three cell types. Exposure to 10<jats:sup><jats:italic>\u2212<\/jats:italic>7<\/jats:sup>\u00a0mol\/L of 1\u03b1,25(<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>)<jats:sub>2<\/jats:sub><jats:styled-content style=\"fixed-case\">D<\/jats:styled-content><jats:sub>3<\/jats:sub> (<jats:styled-content style=\"fixed-case\">VD<\/jats:styled-content><jats:sub>3<\/jats:sub>) or tacalcitol suppressed the growth of fibroblasts and mast cells, but not Schwann cells. These results suggest that the different neurofibroma cell types show different responses to <jats:styled-content style=\"fixed-case\">VD<\/jats:styled-content><jats:sub>3<\/jats:sub>. A combination of excimer light irradiation and <jats:styled-content style=\"fixed-case\">VD<\/jats:styled-content><jats:sub>3<\/jats:sub> is necessary to suppress the growth of neurofibroma cells <jats:italic>in vivo<\/jats:italic>.<\/jats:p>","DOI":"10.1111\/1346-8138.12242","type":"journal-article","created":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T06:46:51Z","timestamp":1373957211000},"page":"743-745","source":"Crossref","is-referenced-by-count":4,"title":["<i>In vitro<\/i> responses of neurofibroma fibroblasts, mast cells and <scp>S<\/scp>chwann cells obtained from patients with neurofibromatosis 1 to 308\u2010nm excimer light and\/or vitamin <scp>D<\/scp><sub>3<\/sub>"],"prefix":"10.1111","volume":"40","author":[{"given":"Juichiro","family":"Nakayama","sequence":"first","affiliation":[{"name":"Department of Dermatology Fukuoka University Faculty of Medicine Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiemi","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fukuoka University Faculty of Medicine Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Imafuku","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fukuoka University Faculty of Medicine Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1068452"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddl165"},{"key":"e_1_2_7_4_1","first-page":"202","article-title":"Vitamin D3 analogues improve caf\u00e9 au lait spots in patients with von Recklinghausen's disease: experimental and clinical studies","volume":"9","author":"Nakayama J","year":"1999","journal-title":"Eur J Dermatol"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-1811(98)00033-4"},{"key":"e_1_2_7_6_1","first-page":"169","article-title":"Inhibitory effects of various vitamin D3 analogues on the growth of cells isolated from neurofibromas in patients with von Recklinghausen's neurofibromatosis\u20101","volume":"7","author":"Nakayama J","year":"1997","journal-title":"Eur J Dermatol"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/9.20.3055"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.7.2045"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04960.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4547(19980915)53:6<742::AID-JNR11>3.0.CO;2-#"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5701095"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05283.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12242","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12242","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T14:24:27Z","timestamp":1696256667000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,16]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["10.1111\/1346-8138.12242"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12242","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,16]]}}}