{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:39:47Z","timestamp":1787013587686,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,8,21]],"date-time":"2013-08-21T00:00:00Z","timestamp":1377043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pyoderma gangrenosum is an ulcerative skin disorder showing characteristic non\u2010infectious ulcers and affects the lower extremities in approximately 70% of cases. Pyoderma gangrenosum is commonly associated with systemic diseases such as inflammatory bowel disease, rheumatoid arthritis and hematological malignancies. Herein, we report two cases of Japanese patients diagnosed with genital pyoderma gangrenosum. Case 1 was a 74\u2010year\u2010old woman without associated systemic complications, whose skin lesion resembled a squamous cell carcinoma and was limited to the vulva. Case 2 is an 89\u2010year\u2010old man, who suffered from myelodysplastic syndrome and acute myeloid leukemia, and presented with penile and leg ulcers mimicking pressure sores. Both cases responded well to systemic steroids. We review 13 genital pyoderma gangrenosum cases (76.9% male; aged 30\u201389\u00a0years) from 1996 to 2012 in Japan, including 11 previously reported cases and the present study's two cases. Four of the 13 genital pyoderma gangrenosum cases had associated systemic diseases and their skin lesions spread to the extragenital areas. Eight of the remaining nine genitalia\u2010localized pyoderma gangrenosum cases had no associated systemic diseases. In conclusion, genital pyoderma gangrenosum is rare and may be misdiagnosed. It should therefore be considered in cases of refractory genital ulcers. In addition, genitalia\u2010localized pyoderma gangrenosum tends to be without systemic complications.<\/jats:p>","DOI":"10.1111\/1346-8138.12252","type":"journal-article","created":{"date-parts":[[2013,8,21]],"date-time":"2013-08-21T05:38:49Z","timestamp":1377063529000},"page":"840-843","source":"Crossref","is-referenced-by-count":36,"title":["Genital pyoderma gangrenosum: Report of two cases and published work review of Japanese cases"],"prefix":"10.1111","volume":"40","author":[{"given":"Masataka","family":"Satoh","sequence":"first","affiliation":[{"name":"Department of Dermatology School of Medicine Fukushima Medical University Fukushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Fukushima Medical University Fukushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,8,21]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.01.049"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2012.06.019"},{"key":"e_1_2_5_4_1","first-page":"607","article-title":"A case of pyoderma gangrenosum with IgG \u03bb type monoclonal gammopathy","volume":"50","author":"Sato H","year":"1996","journal-title":"Rinsho Hifuka"},{"key":"e_1_2_5_5_1","first-page":"809","article-title":"A case of pyoderma gangrenosum of penis","volume":"53","author":"Makizumi K","year":"1999","journal-title":"Rinsho Hinyokika"},{"key":"e_1_2_5_6_1","first-page":"610","article-title":"A case of pyoderma gangrenosum with penile ulcer presented as the first sign","volume":"56","author":"Sato K","year":"2002","journal-title":"Rinsho Hifuka"},{"key":"e_1_2_5_7_1","first-page":"411","article-title":"Pyoderma gangrenosum of the penis presenting as fournier's gangrene: a case report","volume":"51","author":"Kohjimoto Y","year":"2005","journal-title":"Hinyokika Kiyo"},{"key":"e_1_2_5_8_1","first-page":"61","article-title":"Pyoderma gangrenosum of the penis","volume":"14","author":"Tabata N","year":"2005","journal-title":"Med J Sendai R C H"},{"key":"e_1_2_5_9_1","first-page":"413","article-title":"PG of the penis leaving scarring deformity","volume":"47","author":"Noda T","year":"2005","journal-title":"Rinsho Derma (Tokyo)"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2008.00468.x"},{"key":"e_1_2_5_11_1","first-page":"173","article-title":"A case of pyoderma gangrenosum","volume":"51","author":"Nakasone Y","year":"2009","journal-title":"Rinsho Derma (Tokyo)"},{"key":"e_1_2_5_12_1","first-page":"80","article-title":"Skin grafting for pyoderma gangrenosum","volume":"64","author":"Ohguchi Y","year":"2010","journal-title":"Rinsho Hifuka"},{"key":"e_1_2_5_13_1","first-page":"924","article-title":"Penile pyoderma gangrenosum","volume":"53","author":"Urano S","year":"2011","journal-title":"Rinsho Derma (Tokyo)"},{"key":"e_1_2_5_14_1","first-page":"687","article-title":"A case of pyoderma gangrenosum on the glans penis","volume":"66","author":"Sato S","year":"2012","journal-title":"Rinsho Hifuka"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2009.24.6.1200"},{"key":"e_1_2_5_16_1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.5070\/D36V51G77T","article-title":"Penile pyoderma gangrenosum","volume":"12","author":"Badgwell C","year":"2006","journal-title":"Dermatol Online J"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2003.00261.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12252","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12252","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T00:01:02Z","timestamp":1696204862000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,21]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1111\/1346-8138.12252"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12252","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,21]]}}}