{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T19:08:07Z","timestamp":1721416087559},"reference-count":8,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,8,21]],"date-time":"2013-08-21T00:00:00Z","timestamp":1377043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The serum vitamin D<jats:sub>3<\/jats:sub> levels in patients with neurofibromatosis 1 has been reported to be significantly lower than that in control subjects, and the level of vitamin D<jats:sub>3<\/jats:sub> reversely correlates with the severity of neurofibroma formation. We found that narrowband ultraviolet <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">NB\u2010UVB<\/jats:styled-content>) irradiation increased the serum level of 1,25(<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>)<jats:sub>2<\/jats:sub> vitamin D<jats:sub>3<\/jats:sub> in patients with neurofibromatosis 1. The difference in the 1,25(<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>)<jats:sub>2<\/jats:sub> vitamin D<jats:sub>3<\/jats:sub> levels between patients who had received irradiation for more than 18\u00a0months and those who had no irradiation was highly significant. Time\u2010course analyses of the serum vitamin D<jats:sub>3<\/jats:sub> levels in the patients who were enrolled after informed consent revealed that the levels became higher significantly after 6\u00a0months of irradiation. It is suggested that <jats:styled-content style=\"fixed-case\">NB\u2010UVB<\/jats:styled-content> irradiation is effective for increasing the serum level of vitamin D<jats:sub>3<\/jats:sub> in patients with neurofibromatosis 1, which may be of benefit for skin symptoms such as pigmented macules or neurofibromas.<\/jats:p>","DOI":"10.1111\/1346-8138.12256","type":"journal-article","created":{"date-parts":[[2013,8,21]],"date-time":"2013-08-21T09:40:51Z","timestamp":1377078051000},"page":"829-831","source":"Crossref","is-referenced-by-count":3,"title":["Narrowband ultraviolet <scp>B<\/scp> irradiation increases the serum level of vitamin <scp>D<\/scp><sub>3<\/sub> in patients with neurofibromatosis 1"],"prefix":"10.1111","volume":"40","author":[{"given":"Juichiro","family":"Nakayama","sequence":"first","affiliation":[{"name":"Department of Dermatology Fukuoka University Faculty of Medicine Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Imafuku","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fukuoka University Faculty of Medicine Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuki","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fukuoka University Faculty of Medicine Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiemi","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fukuoka University Faculty of Medicine Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8,21]]},"reference":[{"key":"e_1_2_6_2_1","article-title":"In vitro responses of neurofibroma fibroblasts, mast cells, and Schwann cells obtained from patients with neurofibromatosis 1 to 308\u2010nm excimer light and\/or vitamin D3","author":"Nakayama J","journal-title":"J Dermatol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2007.00570.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2006.041095"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09767.x"},{"key":"e_1_2_6_6_1","first-page":"202","article-title":"Vitamin D3 analogues improve caf\u00e9 au lait spots in patients with von Recklinghausen's disease: experimental and clinical studies","volume":"9","author":"Nakayama J","year":"1999","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1068452"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-006-0644-6"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05283.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12256","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12256","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T04:00:07Z","timestamp":1696219207000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12256"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,21]]},"references-count":8,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1111\/1346-8138.12256"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12256","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,21]]}}}